Hemostasis Flashcards

1
Q

Coagulation Cascade: What are the Extrinsic Factors?

A

Collagen & Thromboplastins

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2
Q

Coagulation Cascade: What are the Intrinsic Factors?

A

Prothrombin & Fibrinogen

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3
Q

What is the purpose of Thromboplastin?

A

They accelerate the process of fibrin formation

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4
Q

Prothrombin is the inactive form of?

A

Thrombin

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5
Q

What is combined to create the fibrin threads?

A

Thrombin combines with Fibrinogen

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6
Q

How is a fibrin clot created out of fibrin threads?

A

Fibrin incorporate the platelet plug, plasma, & RBC to create the fibrin clot

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7
Q

What is pushed out of the fibrin meshwork when the fibrin clot begins to retract?

A

Serum

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8
Q

What ingredient is needed to break down or dissolve a blood clot?

A

An Enzyme Plasmin also called Fibrinolysin

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9
Q

What is the inactive form of Fibrinolysin?

A

Plasminogen

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10
Q

What is the active form of Plasminogen?

A

Fibrinolysin also called Plasmin

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11
Q

What activates the clot breakdown?

A

The damage tissue and activation of thrombin

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12
Q

What are anti-clotting factors?

A
  1. Heparin is an anticoagulant.
  2. A small amount of Plasmin is always circulating prevents clots
  3. Smooth vessels help prevent platelets from sticking
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13
Q

What are the 2 intravascular clots?

A
  1. Thrombus
  2. Embolus
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14
Q

What is a thrombus clot?

A

The blood clot adheres to a vessel wall

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15
Q

What is an Embolus clot?

A

The blood clot is free floating in the circulatory system (blood stream)

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