Leukocytes Flashcards
Function of leukocytes
defense against disease
Structure of leukocytes
Complete cells, with a nucleus and organelles
List the WBC from most to least abundant
▪ Neutrophils
▪ Lymphocytes
▪ Monocytes
▪ Eosinophils
▪ Basophils
Desc granulocytes (type of leukocytes)
contain granules in cytoplasm
lobed nuclei
Include neutrophils, eosinophils and basophils
Desc Agranulocytes (type of leukocytes)
Lack of cytoplasmic granules
Nuclei are kidney-shaped
Include lymphocytes and monocytes
Leukopoiesis (production of WBC) are stimulated by which chemical messengers
▪ Interleukins (e.g., IL-3, IL-5)
▪ Colony-stimulating factors (CSFs)
which stem cell gives rise to lymphocytes
Lymphoid stem cell
which stem cell gives rise to other lineages
Myeloid stem cell
which WBC FORM PARTIALLY in bone marrow
granulocytes and monocytes
which WBC FORM PARTIALLY in lymph tissue
lymphocytes and plasma cells
shape of granulocytes
Band-shaped
Neutrophils features and function
Size
▪ Twice as large as erythrocytes
Function
▪ Act as phagocytes at active sites of infection
3 to 6 lobes of nuclei
Eosinophils features and function
almost same size with neutrophils
Bilobed (purple) nucleus
Functions
▪ fight against parasitic infections
▪ Response to allergies and asthma
▪ Increase in reaction to cancer and certain drugs
Basophils features and function
Deep purple nucleus large basophilic granules
Function
Initiate inflammation
Histamine: inflammatory chemical that acts as vasodilator to attract WBCs to inflamed sites
Release histamine in allergic reaction
Lymphocytes feature and function
Large, dark-purple, spherical nuclei
Thin rim of pale-blue cytoplasm
Function:
▪ T lymphocytes- attack virus-infected cells and tumour cells
▪ B lymphocytes- give rise to plasma cells, producing antibodies