Leukocytes Flashcards

1
Q

Function of leukocytes

A

defense against disease

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2
Q

Structure of leukocytes

A

Complete cells, with a nucleus and organelles

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3
Q

List the WBC from most to least abundant

A

▪ Neutrophils
▪ Lymphocytes
▪ Monocytes
▪ Eosinophils
▪ Basophils

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4
Q

Desc granulocytes (type of leukocytes)

A

contain granules in cytoplasm
lobed nuclei

Include neutrophils, eosinophils and basophils

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5
Q

Desc Agranulocytes (type of leukocytes)

A

Lack of cytoplasmic granules

Nuclei are kidney-shaped

Include lymphocytes and monocytes

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6
Q

Leukopoiesis (production of WBC) are stimulated by which chemical messengers

A

▪ Interleukins (e.g., IL-3, IL-5)

▪ Colony-stimulating factors (CSFs)

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7
Q

which stem cell gives rise to lymphocytes

A

Lymphoid stem cell

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8
Q

which stem cell gives rise to other lineages

A

Myeloid stem cell

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9
Q

which WBC FORM PARTIALLY in bone marrow

A

granulocytes and monocytes

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10
Q

which WBC FORM PARTIALLY in lymph tissue

A

lymphocytes and plasma cells

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11
Q

shape of granulocytes

A

Band-shaped

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12
Q

Neutrophils features and function

A

Size
▪ Twice as large as erythrocytes

Function
▪ Act as phagocytes at active sites of infection

3 to 6 lobes of nuclei

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13
Q

Eosinophils features and function

A

almost same size with neutrophils

Bilobed (purple) nucleus

Functions
▪ fight against parasitic infections
▪ Response to allergies and asthma
▪ Increase in reaction to cancer and certain drugs

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14
Q

Basophils features and function

A

Deep purple nucleus large basophilic granules

Function
Initiate inflammation

Histamine: inflammatory chemical that acts as vasodilator to attract WBCs to inflamed sites

Release histamine in allergic reaction

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15
Q

Lymphocytes feature and function

A

Large, dark-purple, spherical nuclei

Thin rim of pale-blue cytoplasm

Function:
▪ T lymphocytes- attack virus-infected cells and tumour cells
▪ B lymphocytes- give rise to plasma cells, producing antibodies

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16
Q

Monocytes feature and function

A

Dark-purple nucleus in U or kidney shaped and pale-blue cytoplasm

Function of monocytes
▪ Leave circulation, enter tissues, and differentiate into macrophages
▪ Activate lymphocytes to mount an immune response

17
Q

formation of leukocyte

A

Hematopoietic stem cells differentiate into lymphoid cell in the bone marrow and lymphoid cell develop into different types of white blood cells, like neutrophils, lymphocytes, monocytes, eosinophils, and basophils. These white blood cells help the body fight infections and keep us healthy by defending against germs