Leucémie (4 périodes) Flashcards

1
Q

Deux types de leucémie

A

Myéloïde osseuse aigue
Lymphoïde aigue/chronique

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2
Q

Myéloïde aigue moelle osseuse

A

+++ myéloblastes, mais – granulocytes

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3
Q

Lymphoïde aigue moelle osseuse

A

+++ lymphoblastes mais – lymphocytes

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4
Q

Myéloïde aigue causes (GR)

A

Génétique
Radiations

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5
Q

Lymphoïde aigue causes GGR

A

Gène Philadelphie
Génétique
Radiations

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6
Q

Effets leucémie aigue labos

A

Diminution GB, GR, PLT

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7
Q

Effets systémiques aigue (infiltration) (TSG*)

A

Thymus
Système nerveux
Ganglions
*Splénomégalie -> LLA

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8
Q

Examens diagnostiques (PPFFLÉ)

A

Ponction lombaire
Ponction moelle osseuse
Frottis sanguin
FSC
LDH
Étude génétique

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9
Q

Différences aigue vs chronique (A :ETA) (C : ASA)

A

Aigue :
Enfants
Très rapide
Atteint blastes peu différenciés
Chronique :
Adultes
Subtile
Atteint cellules deja différenciées

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10
Q

5 phases traitement (IPCES)

A

Induction
Prophylaxie
Consolidation
Entretien
Soutien

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11
Q

Leucostase

A

Leucostase : Accumulation anormale GB dans capillaires formant petits caillots blancs

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12
Q

Syndrome de lyse tumorale

A

Lyse cellulaire massive due à accumulation de déchets dans le sang

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13
Q

Lymphome définition

A

Anomalie a/n maturation des lymphocytes une fois dans le syst lymph

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14
Q

Lymphome Hodgkinien cellules

A

différenciation des cellules ne se complète jamais

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15
Q

Lymphome non Hodgkinien

A

Lymphome normal

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16
Q

Causes lymph. Hodgkinien (EMAH)

A

Exposition virus (mono VIH)
Maladies autoimmune
Âge
Hérédité

17
Q

Causes lymphome non hodgkinien (VV)

A

Virus Epstein-Barr
Virus bizarre

18
Q
A