LET, OER, RBE Flashcards
For a given particle, LET _____ with higher energy
decreases
LET of 75 MeV argon
250 … VERY high
LET of 18 MeV carbon
108
LET of 2.5 alpha particles
170
carbon ion RBE
D250/D(r)
D250 = dose of 250 kV x-rays
D(r) = equivalent dose to achieve same effect
Carbon ion RBE in ____ in hypoxic vs aerated conditions
higher
Densely or Sparsely ionizing?
B particles
sbarsely
Densely or Sparsely ionizing?
a particles
densely
Densely or Sparsely ionizing?
gamma particles
sparsely ionizing along tracks of electrons
However I-125 decay is electron capture followed by gamma decay at very low energy and thus is densely ionizing.
What can assay the extent and location of hypoxia in tumors?
EPR imaging - electron paramagnetic resonance imaging
OER of X-rays
2-3.5
Higher at high doses
lower at low doses
what stains hypoxia
pimonidazole