Lesson 7 - The Cerebellum Flashcards

1
Q

The cerebellum is ? gms, ?/10 of adult brain

A

150 gms, 1/10 of adult brain

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2
Q

The cerebellum is bilaterally ————- with an extensive cortex: ½ that of
cerebral cortex and with 3.6 x the number of neurons

A

symmetrical

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3
Q

The cerebellum is located in ———— ————— ———
* ———— ———— (cerebrum), 4th ventricle (brainstem)

A

posterior cranial fossa
tentorium cerebelli

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4
Q

The cerebellum communicates with brainstem via superior , middle, and inferior ——– —————s

A

cerebellar peduncles

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5
Q

The cerebellum functions in:
* gait and ————–
* ————- of movements
* precision and accuracy of movement
* ———- learning
* reflex modification

A

balance
coordination
motor

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6
Q

Longitudinal divisions of the cerebellum

  • Vermis
    – ———— region
    – ————- Hemispheres
A

Paravermal
Cerebellar

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7
Q

Transverse divisions of the cerebellum:

Anterior lobe
* ————– fissure– Posterior (or Middle) lobe
* Posterolateral fissure– —————- lobe

A

Primary
Flocculonodular

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8
Q

————– peduncle –sup pons/ midbrain
———— peduncle –pons
————– peduncle -medull

A

Superior
Middle
Inferior

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9
Q

Superior cerebellar peduncle –sup pons/ midbrain
* ————– projections

A

Efferent

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10
Q

Middle peduncle –pons
* ————— projections

A

Afferent

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11
Q

Inferior peduncle –medulla
* ———- and ———— projections

A

afferent and efferent

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12
Q

Cerebellum Lobules:

The lobule just rostral of the 4th ventricle is I and the one just caudal to it is X

Between lobules V and VI is the primary fissure and separates the posterior lobe from the
anterior lobe

The tonsils are clinically important due to their proximity to the ————— ————–

A

reticular formation

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13
Q

Cerebellar Nuclei:
4 nuclei:

Lateral –> Medial

– Dentate
* ————– Hemisphere

– Emboliform (Interposed
nuclei)
* ————– zone

– Globose (Interposed
nuclei)
* ————- zone

– Fastigial
* ————

A

Cerebellar
Paramedian
Paramedian
Vermis

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14
Q

What are the 3 Cerebellar cortex layers?

A

1) Molecular– 2) Purkinje– 3) Granule

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15
Q

What are the 5 cell types of the cerebellar cortex?

A

5 cell types:
Purkinje ([ ([–], Efferents)
Granule ([+], target of Mossy)
Stellate ([ ([–], inhibit nearby Purkinje)
Basket ([ ([–], inhibit distant Purkinje)
Golgi ([ ([–], inhibit Granule cells)

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16
Q

Name 2 fibres of the cerebellar cortex

A

2 fibers
– Mossy fiber ([+], Afferents from cortex, brainstem trigeminal nerve, vestibular nerve and nuclei, reticular
nuclei and spinal cord cuneate and gracile)
– Climbing fiber ([+], Afferents, only from inferior olive)

17
Q

Functional divisions of the cerebellum:

– AKA Archicerebellum
– Regulates balance and reflex eye movements

– AKA Paleocerebellum
– Adjust ongoing movements and controls muscle tone
– Stance and gait

– AKA Neocerebellum
– Planning and initiation of skilled movements, smooth and
precise control

A

Vestibulocerebellum

Spinocerebellum

Cerebrocerebellum

18
Q

Circuitry:
projections to the cerebellum:

Input from the frontal and parietal cortices is relayed to the pons (i.e. pontocerebellar tract), and thereafter to the
———— ————— via the middle cerebellar ————

Sensory input from the vestibular and reticular nuclei, inferior olives and the dorsal nuclei of Clark is relayed to
the cerebellar cortex via the inferior cerebellar ————s

A

cerebellar cortex
peduncle

peduncles

19
Q

Circuitry:
projections from the cerebellum:

Information sent to the ———- nuclei exits
the cerebellum via the ———- —————–
peduncle and is relayed to the vestibular
nuclei

Information sent to the globes, ———– and ————– nuclei exits the cerebellum via
the superior cerebellar peduncle and is
relayed to the thalamus and the motor cortex

A

fastigial
inferior cerebellar
emboliform and dentate

20
Q

The Somatotopy of the ————— is not as clearly organized and orderly as that in motor and somatosensory cortex,
but does exist

A

Spinocerebellum

21
Q

The superior cerebellar peduncle is the primary ———- pathway from the deep cerebellar
nuclei

22
Q

The middle cerebellar peduncle is an ———- pathway from the cerebral cortex

23
Q

The inferior cerebellar peduncle provides —————- from the spinal cord, brainstem and inferior olive AND ——– to the brainstem

A

input
output

24
Q

Outputs travel via superior and inferior peduncles to terminate in 4 mains structures that
send tracts down the spinal cord to influence spinal motor neurons:
1. Motor regions of cerebral cortex (via thalamus relay)
2. —– nucleus
3. ————- nuclei
4. ————- nuclei

A

Red
Vestibular
Reticular

25
The cerebellum displays ----------- control (i.e., controls movement on the same side of the body, since all pathways project ipsilaterally, bilaterally or double cross)
IPSILATERAL
26
Name some symptoms of cerebellar dysfunction (Unilateral lesions produce ipsilateral symptoms)
Intention tremor Gait ataxia Trucal ataxia Dysmetria
27
Causes of cerebellar dysfunction?
– Physical trauma – Interruption of blood supply/stroke (AICA , PICA) – Alcoholism (affects Purkinje cells in anterior lobe) – Tumours/ cancer (degeneration of Purkinje cells
28
What is the clinical presentation of cerebellar dysfunction?
Clinical Presentation ‘DANISH’* – D : Dysdiadochokinesia (difficulty in carrying out rapid, alternating movements) – A: Ataxia – N : Nystagmus (coarse) – I: Intention tremor – S: Scanning speech – H: Hypotonia