Lesson 6: Parvoviridae

Question 1

General description of parvoviridae

Answer 1

✓ Small, non-enveloped, single-stranded DNA viruses
✓ Icosahedral symmetry
✓ Replicate in the nucleus, form intranuclear inclusion bodies
✓ Require rapidly dividing cells for replication
✓ Stable in the environment
✓ Resistant to heat, solvents, disinfectants and pH changes

Question 2

Genus parvovirus;

Answer 2

✓ many have hemagglutinating activity
✓ shed in large numbers in faeces
✓ enteric and systemic diseases in dogs and cats
✓ reproductive failure, SMEDI syndrome in pigs

Question 3

also know as feline infectious enteritis or feline distemper. one of the most common feline viral infections

Answer 3

Feline panleukopenia virus

Question 4

disease in dogs with high morbidity and mortality

Answer 4

Canine parvovirus

Question 5

Three subtypes of canine parvovirus

Answer 5

CPV- 2a, CPV- 2b and CPV- 2c

Question 6

Highly contagious systemic and enteric disease most common in weaned kittens, manifested by depression, diarrhoea, intrauterine infection, abortion or cerebellar ataxia in neonatal kittens

Answer 6

Feline panleukopenia virus

Question 7

Highly contagious enteric disease with depression, vomiting, dysentery and immunosuppression. intrauterine or perinatal infection; myocarditis in pups (rare)

Answer 7

canine parvovirus (CPV2)

Question 8

major cause of still births, mummified foetuses, embryonic deaths and infertility (SMEDI syndrome)

Answer 8

Porcine parvovirus

Question 9

Generalized disease of mink kits, analogous to feline panleukopenia

Answer 9

Mink enteritis virus

Question 10

Chronic progressive disease of mink homozygous for pale coat colour. persistent viraemia, plasmacytosis, hypergammaglobulinaemia and immune complex related lesions.

Answer 10

aleutian mink disease virus

Question 11

highly contagious, fatal disease of 8 to 30 day old goslings

Answer 11

Goose parvovirus

Question 12

another term of goose parvovirus

Answer 12

goose plague virus

Question 13

what disease is highly contagious, fatal disease of 8 to 30-day old goslings

Answer 13

Derzsy’s disease

Question 14

High mortality, clinical signs and lesions similar to goose parvovirus

Answer 14

Duck parvovirus

Question 15

Role of virus in disease is uncertain; serological surveys suggest the virus is widespread

Answer 15

Canine minute virus

Question 16

Other term of canine minute virus?

Answer 16

canine parvovirus 1

Question 17

associated with sporadic outbreaks of diarrhoea in calves

Answer 17

Bovine parvovirus

Question 18

may act as mechanical vectors of feline panleukopenia virus

Answer 18

fleas and humans

Question 19

Diagnosis of Feline panleukopenia virus

Answer 19

Serology (ELISA, canine parvovirus kit may be used, VNT) PCR

Question 20

Control in Feline panleukopenia virus

Answer 20

vaccines are available, disinfection in contaminated area

Question 21

acute enteric disease natural exposure and vaccination confers immunity in the adult dog thus clinical presentation is common in?

Answer 21

young dogs between weaning and 6 months of age

Question 22

Transmission of Canine parvovirus

Answer 22

oro-fecal route, mechanical transfer (vectors)

Question 23

Diagnosis for Canine parvovirus

Answer 23

specimen to be collected are faeces, blood and affected tissues (intestines and myocardium), leukopenia, pr basophilic inclusion bodies in cardiac myocytes. Commercial test kit

Question 24

an important cause of reproductive failure in pigs

Answer 24

porcine parvovirus

Question 25

it causes erythema infection (fifth disease or “slapped cheek” disease) in children and spread from person to person and most often results is no or very mild symptoms

Answer 25

Human parvovirus B19