Lesson 6: Parvoviridae Flashcards
General description of parvoviridae
✓ Small, non-enveloped, single-stranded DNA viruses
✓ Icosahedral symmetry
✓ Replicate in the nucleus, form intranuclear inclusion bodies
✓ Require rapidly dividing cells for replication
✓ Stable in the environment
✓ Resistant to heat, solvents, disinfectants and pH changes
Genus parvovirus;
✓ many have hemagglutinating activity
✓ shed in large numbers in faeces
✓ enteric and systemic diseases in dogs and cats
✓ reproductive failure, SMEDI syndrome in pigs
also know as feline infectious enteritis or feline distemper. one of the most common feline viral infections
Feline panleukopenia virus
disease in dogs with high morbidity and mortality
Canine parvovirus
Three subtypes of canine parvovirus
CPV- 2a, CPV- 2b and CPV- 2c
Highly contagious systemic and enteric disease most common in weaned kittens, manifested by depression, diarrhoea, intrauterine infection, abortion or cerebellar ataxia in neonatal kittens
Feline panleukopenia virus
Highly contagious enteric disease with depression, vomiting, dysentery and immunosuppression. intrauterine or perinatal infection; myocarditis in pups (rare)
canine parvovirus (CPV2)
major cause of still births, mummified foetuses, embryonic deaths and infertility (SMEDI syndrome)
Porcine parvovirus
Generalized disease of mink kits, analogous to feline panleukopenia
Mink enteritis virus
Chronic progressive disease of mink homozygous for pale coat colour. persistent viraemia, plasmacytosis, hypergammaglobulinaemia and immune complex related lesions.
aleutian mink disease virus
highly contagious, fatal disease of 8 to 30 day old goslings
Goose parvovirus
another term of goose parvovirus
goose plague virus
what disease is highly contagious, fatal disease of 8 to 30-day old goslings
Derzsy’s disease
High mortality, clinical signs and lesions similar to goose parvovirus
Duck parvovirus
Role of virus in disease is uncertain; serological surveys suggest the virus is widespread
Canine minute virus
Other term of canine minute virus?
canine parvovirus 1
associated with sporadic outbreaks of diarrhoea in calves
Bovine parvovirus
may act as mechanical vectors of feline panleukopenia virus
fleas and humans
Diagnosis of Feline panleukopenia virus
Serology (ELISA, canine parvovirus kit may be used, VNT) PCR
Control in Feline panleukopenia virus
vaccines are available, disinfection in contaminated area
acute enteric disease natural exposure and vaccination confers immunity in the adult dog thus clinical presentation is common in?
young dogs between weaning and 6 months of age
Transmission of Canine parvovirus
oro-fecal route, mechanical transfer (vectors)
Diagnosis for Canine parvovirus
specimen to be collected are faeces, blood and affected tissues (intestines and myocardium), leukopenia, pr basophilic inclusion bodies in cardiac myocytes. Commercial test kit
an important cause of reproductive failure in pigs
porcine parvovirus
it causes erythema infection (fifth disease or “slapped cheek” disease) in children and spread from person to person and most often results is no or very mild symptoms
Human parvovirus B19
