Lesson 6 (Biosafety and Biosecurity) Flashcards

1
Q

What do you call the pathogens that are commonly acquired

A

Laboratory Acquired Infections (LAI)

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2
Q

Protecting people from dangerous pathogens

A

Biosafety

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3
Q

Protecting pathogens from dangerous people

A

Biosecurity

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4
Q

When and where did the history of laboratory biosafety took place

A

North America and West Europe (1943)

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5
Q

The first person who created the Biological Development/ Biological Weapons Program

A

Franklin Roosevelt

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6
Q

When did he create the Biological Weapon Program

A

during cold war

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7
Q

(blank) focused only on the biological usage or microorganism that are against the (blank)

A

Biological Program; Soviet Union

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8
Q

The first scientific director in 1943 of Camp Detrick

A

Ira L. Baldwin

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9
Q

The center of the US Biological Program and also the designated installation for Biological Research and Development

A

Camp Detrick

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10
Q

new name for Camp Detrick

A

Fort Detrick

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11
Q

Designed multiplications for Biosafety at Camp Detrick

A

Newell Johnson

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12
Q

The meetings of Johnson eventually lead to (blank)

A

The American Biological Safety Association (ABSA)

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13
Q

He terminated the Biological Program that created by Roosevelt + (what year)

A

Richard Nixon in 1969

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14
Q

First person who invented the Mechanical Pipettor

A

Arnold Wedum

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15
Q

Another invention of Arnold Wedum

A

Ventilation Cabinet to prevent infection against MTB or Macrobacterium Tuberculosis

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16
Q

Defined as any biological or chemical substance that is dangerous to
human, animals or the environment

A

Biohazard

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17
Q

Examples of biohazard

A

body fluids, human tissue and blood, and recombinant DNA

18
Q

Used universally to report Harmful substances that are particularly
dangerous for living beings

A

Biohazard symbol

19
Q

Who created the Biohazard symbol (year)

A

Charles Baldwin (1966)

20
Q

Agents that are not associated with disease in healthy adult
humans. The low individual and community risk.

21
Q

Agents that are associated with human disease which is
rarely serious and for which preventive or therapeutic inventions are
often available. Moderate individual and low community risk.

22
Q

Agents that are associated with serious or lethal human
disease for which preventive or therapeutic or interventions may be
available. High individual risk but low community risk.

23
Q

Agents that are likely to cause serios or lethal human disease
for which preventive or therapeutic inventions are not usually
available. High individual risk and high transmissible to an
individual.

24
Q

Suitable for work involving variable microorganism that are defined
and well characterized strains known not to cause disease in human; appropriate among undergraduate and secondary educational
training and teaching laboratories that require basic lab safety
practices; no containment needed

A

Biosafety lvl 1

25
Containment for Biosafety lvl 1
no containment needed
26
Ex. for biosafety lvl 1
Bacillus subtilis, Naegleria gruberi, Infectious canine hepatitis virus
26
Risk Group 1 Organism
E coli K-21 Transgenic Plants Plasmids Fungi Molds Yeast
27
For lab that deals with indigenous MODERATE RISK agents; lab consequently observing good microbial techniques; when handling human blood, body fluid, tissues where there is uncertain presence of infections agents; handwashing sinks and waste decontamination facility
Biosafety lvl 2
28
Containment for Biosafety lvl 2
biosafety cabinets
29
Ex. for biosafety lvl 2
Hepa B, HIV Salmonella, Toxoplasma
30
Risk Group 2 Organism
Human or Primate Cells Herpes simplex Virus Replication Incompetent Attended Human Immunodeficiency Virus Patient specimens
31
Primary and secondary barriers in the protections of the personnel from infectious aerosol exposure; indigenous or toxic agents with potential for respiratory transmission that may cause serious and lethal infections
Biosafety lvl 3
32
Ex. for biosafety lvl 3
MTB, St. louis Encephalitis Virus
33
Risk Group 3 Organisms
Human Immunodeficiency Virus Mycobacterium Tuberculosis Coxiella Bumetii
34
Dangerous and exotic agents that pose high individual risk of life-threatening disease that may be transmitted via aerosol No vaccine or treatment Separate building or completely isolated zone Builds on BSL-3 / ABSL-3 practices
Biosafety lvl 4
35
Containment for Biosafety lvl 4
BSL-3 + Class III Biosafety Cabinet
36
Risk Group 4 Organisms
Lassa Fever Virus Ebola Hemorrhagic Fever Virus Marburg Virus Herpes B Virus
37
meaning of HEPA filtered air
High Efficiency Particulate Air
38
Provides protection foe the user and surrounding environment, but no protection for the sample being manipulated
Biosafety Cabinets Class 1
39
provides protections for the user, environment and sample, and divides into four types: A1, A2, B3 and B2. The main difference are their minimum inflow velocities and exhaust system
Biosafety Cabinet Class 2
40
Also known as gloves boxes Provides maximum protections; he enclosure is gas light and all materials enter leave through a dunk tank or double door autoclave
Biosafety Cabinet Class 3