Lesson 6 Flashcards
on going replacement of old bone tissue by new bone tissue
bone remodeling
removal of minerals and collagen fibers from bone by osteoclasts
Bone resorption
attaches tightly to the bone surface at the endosteum or periosteum during the process of bone resorption
osteoclasts
enhances synthesis of the proteins needed to build new bone
Nutrition
from pancreas that promotes bone growth by increasing the synthesis of bone proteins
insulin
destruction of bone extracellular matrix
bone resorption
addition of minerals and clagen fibers to bone by osteoblasts
bone deposition
results in formation of bone extracellular matrix
bone deposition
about how many percent of the total bone mass in the body is being remodeled
5%
bone remodeling may be triggered by factors such as
exercise, sedentary lifestyle, changes in diet
Process of Bone Resorption
Quiescent
Activation
Resorption
Formation
Mineralisation
Factors affecting bone growth and bone remodeling
MVH
- intake of Minerals
- intake of Vitamins
- Hormones
necessary during bone remodeling
Minerals, like calcium and phosphorus as well as magnesium, flouride, maganese
stimulates activity of osteoblasts
Vitamin A
needes for synthesis of collagen
Vitamin C
main bone protein
Collagen
- produced by the liver and bone tissue
- stimulate osteoblasts, promotes cell division
IGFs - Insulin like growth factors
from thyroid gland
thyroid hormones (T3 and T4)
- from pancreas
Insulin
- causes dramatic effect on bone growth
sex hormones
contribute to bone remodeling by slowing bone resorption of old bone and promoting deposition of new bone
sex hormones
programmed death of osteoclasts
apoptosis
stimulate bone growth
insulin like growth factors
human growth hormone
thyroid hormones
insulin
needed fo bone growth and maintenance
dietary minerals - ca and phosphorus
vitamins - A, C, D, K and B12
