LESSON 5: CIRCOVIRIDAE

Question 1

Circoviridae
General description

Answer 1

circular single-stranded DNA
 non-enveloped with icosahedral symmetry

Question 2

stable in the environment at pH

Answer 2

3 to pH 9

Question 3

resists heating at

Answer 3

60°C for 30 minutes

Question 4

Clinical infestations

Answer 4

1.Chicken anemia virus : or CAV
2. Porcine circovirus 2 (PCV 2)

Question 5

Chickenanemia virus : or CAV, affects young birds worldwide, resulting to

Answer 5

aplastic anaemia and generalized lymphoid atrophy

Question 6

Affected birds are

Answer 6

depressed, anorexic and pale affecting weight gains

Question 7

Transmission:

Answer 7

-orizontal (oro-faecal route) and
-vertical (thru the
eggs) occur

Question 8

Infected poultry viremia, and sheds virus fo

Answer 8

3-4 weeks following
infection

Question 9

Porcine circovirus 2 (PCV 2): associated with

Answer 9

with postweaning multisystemic
wasting syndrome (PMWS),
porcine dermatitis and
nephropathy syndrome

Question 9

Control

Answer 9

: biosecurity, and vaccine are available

Question 9

Diagnosis: to confirm infection with

Answer 9

h PCV 2

Question 9

 Threegenotypes are recognized:

Answer 9

PCV-2a, PCV-2b and PCV-2c

Question 10

, demonstration of the
virus by serology

Answer 10

(ELISA, indirect immunoflourescence)