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AA3 Bacteriology and Mycology > Lesson 4a, 4b, 4c > Flashcards

Lesson 4a, 4b, 4c Flashcards

1
Q

Ingestion of feed contaminated with L. monocytogenes result to

A

septicemia, encephalitis, abortion

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2
Q

L. monocytogenes infection in pregnant animals results to?

A

transplacental transmission

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3
Q

Main route of neural listerioses

A

migration in cranial nerves via dental pulp

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4
Q

What is a major way L. monocytogenes survives within the hosts cell?

A

inhibiting cell autophagy

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5
Q

Its clinical manifestations in ruminants present as encephalitis, abortion, septicemia or endophthalmitis

A

Bovine listeriosis

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6
Q

A form of bovine listeriosis manifested as dullness, circling and tilting of the head, and unilateral facial paralysis:

A

Neural listeriosis

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7
Q

The incubation period of neural listeriosis:

A

14-40 days

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8
Q

The incubation period of septicemic listeriosis:

A

2-3 days

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9
Q

Occur singly, in palisades of parallel cells and in angular clusters resembling Chinese characters in stained smears

A

Corynebacterium species

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10
Q

What is the effect of Corynebacterium bovis in cattle and give their usual habitat

A

subclinical mastitis - teat cistern

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11
Q

C. diptheriae effects on horses

A

wound infection

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12
Q

Which Corynebacterium spp cause abscesses, foci in liver, lungs and lymph nodes in lab rodents?

A

Corynebacterium kutscheri

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13
Q

Non nitrate reducing C. pseudotuberculosis effect on sheep and goats

A

Caseous lymphadenitis

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14
Q

Nitrate reducing biotype of C. pseudotuberculosis effects in horses and cattle

A

Ulcerative lymphagitis, abscess

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15
Q

C. renale effect on cattle

A

Cystitis, pyelonephritis

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16
Q

C. renale effect on sheep and goats

A

ulcerative balanoposthitis

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17
Q

C. pilosum effect on cattle

A

cystitis, pyelonephritis

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18
Q

C. cystidis effect on cattle

A

severe cystitis, pyelonephritis

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19
Q

C. ulcerans effect on cattle

A

mastitis

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20
Q

C. ulcerans effect on cats

A

upper respiratory tract infection

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21
Q

C. ulcerans effects in humans

A

diptheria

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22
Q

Corynebacterium are opportunistic pathogens and pyogenic except for?

A

C. bovis

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23
Q

a facultative intracellular pathogen capable of surviving and replicating in phagocytes whose virulence is linked to its cell wall lipid and to the production of an exotoxin, phospholipase D (PLD) that enhances its survival and multiplication in the host

A

Corynebacterium pseudotuberculosis

24
Q

diptheria toxin from these Corynebacteria species present in raw milk cows may implicate public health

A

Corynebacterium ulcerans, Corynebacterium pseudotuberculosis

25
Q

Encapsulated abscess formation which have an onion ring appearance in cross-section

A

caseous lymphadenitis

26
Q

Also called “pizzle rot” common in Merino sheep and Angora goats

A

Ulcerative balanoposthitis

27
Q

characterized by ulceration around the preputial orifice (or vulva in ewes), with a brownish crust developing over the lesion

A

pizzle rot

28
Q

Formerly named Corynebacterium equi

A

Rhodococcus equi

29
Q

Clinical conditions associated with Rhodococcus equi in humans

30
Q

Clinical conditions associated with Rhodococcus equi in cats

A

subcutaneous abscess, mediastinal granulomas

31
Q

Clinical conditions associated with Rhodococcus equi in pigs and cattle

A

mild cervical lymphadenopathy

32
Q

Clinical conditions associated with Rhodococcus equi in horses

A

superficial abcessation

33
Q

Oppurtunistic intracellular pathogen (foal under 6 months old)

A

Rhodococcus equi

34
Q

Clinical conditions associated with Rhodococcus equi in foals 1-4 mos old

A

Suppurative bronchopneumonia and pulmonary abscessation

35
Q

epidemiology of suppurative bronchopneumonia of foals

A

inhalation of contaminated dust or ingestion (sputum) of large numbers of R. equi

36
Q

What is the characteristic microscopic morphology of Corynebacterium species in stained smears?

A

Gram-positive pleomorphic bacteria in palisades or angular clusters

37
Q

Which Corynebacterium species is notable for not being an opportunistic pyogenic pathogen, unlike most others in the genus?

A

Corynebacterium bovis

38
Q

What exotoxin, produced by Corynebacterium pseudotuberculosis, enhances its survival and multiplication in the host by disrupting phagocyte membranes?

A

Phospholipase D (PLD)

39
Q

What is the characteristic lesion observed in caseous lymphadenitis caused by C. pseudotuberculosis?

A

Encapsulated abscesses with an “onion ring” appearance

40
Q

Which Corynebacterium species is associated with ulcerative lymphangitis in horses and cattle?

A

C. pseudotuberculosis (nitrate-reducing biotype)

41
Q

What predisposing factor in cows makes them susceptible to bovine pyelonephritis caused by the C. renale group?

A

Stress of parturition and short urethra

42
Q

What diagnostic method is used to detect antibodies against C. pseudotuberculosis in caseous lymphadenitis?

43
Q

What is the primary habitat of Rhodococcus equi?

A

Soil (saprophyte)

44
Q

What age group of foals is most susceptible to suppurative bronchopneumonia caused by Rhodococcus equi?

A

Foals under 6 months old

45
Q

What virulence factor of Rhodococcus equi is encoded by a large plasmid and used as an epidemiological marker?

A

VapA protein

46
Q

What is the result of R. equi cultured on MacConkey agar?

47
Q

What test is R. equi positive for?

a) Oxidase test
b) CAMP test
c) Catalase test
d) Sugar fermentation test.

48
Q

What is the typical microscopic morphology of Listeria monocytogenes?

A

Gram-positive coccobacillary rods

49
Q

What environmental source is often associated with outbreaks of listeriosis?

A

Silage feeding

50
Q

What is the primary mechanism by which Listeria monocytogenes survives and replicates intracellularly?

a) Formation of inclusion bodies
b) Production of listeriolysin and ActA protein
c) Encapsulation
d) Sporulation

A

Production of listeriolysin and ActA protein

51
Q

What is the role of listeriolysin in Listeria monocytogenes pathogenesis?

a) Adherence to host cells
b) Destruction of phagocytic vacuole membranes
c) Inhibition of complement activation
d) Stimulation of cytokine production

A

Destruction of phagocytic vacuole membranes

52
Q

What are the common clinical manifestations of bovine listeriosis?

A

Encephalitis, abortion, septicemia, and endophthalmitis

53
Q

What characteristic motility is observed in Listeria monocytogenes at 25°C?

A

Tumbling motility

54
Q

What is the primary route of infection for neural listeriosis in sheep?

a) Inhalation of contaminated dust
b) Penetration via the dental pulp and migration in cranial nerves
c) Ingestion of contaminated water
d) Vector-borne transmission

A

Penetration via the dental pulp and migration in cranial nerves

55
Q

What is the result of Listeria spp. cultured on Blood agar?

A

Large beta-hemolytic colonies

56
Q

Give the three species forming the Corynebacterium renale group

A

Corynebacterium renale
Corynebacterium pilosum
Corynebacterium cystidis

57
Q

Habitat of C. renale in sheep and goats

AA3 Bacteriology and Mycology (13 decks)

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