LESSON 2: THE CELL CYCLE Flashcards
- sequence of growth and division of a cell
- name we give the process through which cells replicate and 2 new cells
- has different stages: G1, S, G2, and M
cell cycle
- process that enables cells to change and acquire specific structures and functions
- importance:
- development
- maintenance
- tissue repair
cell modification
- has 3 types:
- differentiation
- specialization
- adaption
- less specialized cell to a more specialized cell
e.g, embryonic development (stem cell > nerve cell)
tissue regeneration (cells in tissue like skin can differentiate to replace damaged cells)
stem cell > muscle/fat/bone/blood/nervous/epithelial/immune/sex cell
differentiation
- cell develops specific structures and functions tailored to perform particular tasks
e.g, RBC ( O transport due to presence of hemogoblin)
neurons ( transmits nerve impulses)
specialization
- modifications in a cell
- undergoes in response to environmental changes
e.g, muscle cells (mitochondria increases, physical activity increases)
adaption
cell modification according to location
top: apical
mid: lateral
bot: basal
- found on apical surface of the cell
apical modification
- locomotion
- formed from microtubules
cilia & flagella
move cell / engulf prey
pseudopods
- found in intestines (bowel movement)
villi & microvilli
- compound secreted by the cell on its apical surface
- glycoprotein = main ingredient
extracellular matrix (ecm)
- desmosomes/hemidesmosomes
- like an anchor on basal surface of the cell
- connects ecm
basal modification
found on basal surface of the cell
lateral modification
lateral modification:
- prevent leakage of ecf (extracellular fluid)
- regulate movement of water and solutes between epithelial layers
tight junction
lateral modification:
- fasten cells like stapler
adhering junction
communicating junctions
e.g,: plants: xylem, phloem: H2O and nutrients transport
guard cell: regulates gas exchange and H2O loss
animals: bone cells (osteocytes): maintain bone structure
skin cells (keratinocytes): form protective barrier
gap junctions
implications of cell modification
development processes: formation of tissues & organs
diseases & disorders
tissue engineering
- cells grow, organelles double prior to the actual
- 95% of the cells’ life is spent here
- has 3 parts
- Growth 1 (G1)
- Synthesis (S)
- Growth 2 (G2)
- lasts 3-15 hours
interphase
-organelles double
-each cell needs a complete set of organelles
g1
-dna is replicated
-each cell needs a complete and identical set of DNA
s
-proteins needed for mitosis are produced
g2
- doubles and separates during mitosis
- chromatin is packed here
- dna is tangled to a substance of chromatin
- structures of tightly packed dna
chromosomes
- process by which the cell nucleus divides into 2 identical nuclei
- “identical twins”
- only lasts 7hrs
- occurs in steps:
- prophase
- metaphase
- anaphase
- telophase
- cytokineses
mitosis
- shortest phase, 2 events only
1. chromosomes line up across middle of the cell
2. spindle fibers connect
metaphase