Lesson 2 Flashcards

1
Q

Reversible process between drugs and protein carrier

A

Distribution

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2
Q

Irreversible loss drug in the body

A

Elimination

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3
Q

Eliminate 1 that is not included in factors that influence drug metabolism
1. Age
2. Tissue depo
3. Genetic factor
4. Change in metabolism rate ( Enzyme induction and Enzyme inhibitor)

A

2

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4
Q

Drug + Receptor + Intrinsic activity

A

= Agonist

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5
Q

Drug+p + Receptor + No intrinsic activity

A

Antagonist

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6
Q

What is idiosyncrinsy

A

Unusual response to drug

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7
Q

Measurement of drugs in lne with safety

A

Therapeutic Index

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8
Q

Concurrent to produce effect

A

Potency

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9
Q

Maximal response

A

Efficacy

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10
Q

Combination of drugs

A

Seniment

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11
Q

Eliminate 1 that is not included in Mechanism of drug action
1. Interaction with receptor
2. Interaction with Enzyme
3. Interaction with membrane phase
4. Interaction with DNA and RNA
5. Inhibition of ChOn (protein)
6. Interaction with cell membrane

A

3

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12
Q

Effect of medication that is not in medication

A

Placebo effect

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13
Q

1 + 1 = 2

A

Addition

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14
Q

1 + 1 = 3 or more

A

Synergism

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15
Q

0 + 1 = 2 or more

A

Potentations

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16
Q

1 + 1 = 0

A

Antagonism

17
Q

Where is cell membrane located?

A

Parietal cells in the stomach

18
Q

What are the Clinicate stage from Phase 1-4?

A
  1. Is the drug safe
  2. Is the drugs working
  3. How well does it work?
  4. Post marketing studies