Lesson 1 Flashcards
There are more or less ___ muscles in the human body
600
Study of the muscular system
Myology
an organ system that permits movement in the body, maintains posture and circulates blood throughout the body
Muscular System
Three types of muscles
Skeletal
Cardiac
Smooth
Properties of Muscles
Excitability/Irritability
Contractility
Extensibility
Elasticity
Tonicity
receive and respond to stimulus
Excitability/Irritability
to shorten and tighten
Contractility
stretch or extend upon the application of force
Extensibility
regain the original shape and size after being stretched
Elasticity
to steadily contract
Tonicity
Function of Muscles
M-H-A-P-P:
Movement
Heat Production
Alters diameters of tubes and vessels in the body
Posture
Protection of vital organs
How many % of body heat is derived from muscle contraction
85%
Two types of muscles according to the type of action:
Voluntary - can be made contract
Involuntary - can’t be controlled by the will
Muscle cells composition
-75% water for hydration
-20% CHON for repair and energy production
-5% Glycogen for ATP production
Voluntary and striated
40% of TBW
Ability to contract, cause and stop movement
Example: breathing and speech, making facial expression
Skeletal Muscles
With alternating ight and dark bands
Characteristics:
Striated
entire heart contracts as one unit
syncytium
Other term for cardiac muscle
Cardiocytes/Heart muscles
Cardiac muscles has the length of and diameter of:
Length: 50-100
Diameter: 10-20
Involuntary
Striated
Autorhythmic
Cardiac muscles
The heart beats ________ per day
100,000
contraction of muscle without apparent stimulation or without frank stimulation
Autorhythmicity
muscle fibers are multinucleated structures
Skeletal Muscles
fibers have one to two nuclei and are physically and electrically connected to each other
Cardiac Muscles
Involuntary
non-striated
fibers are small, spindled-shape, mononucleated with lesser actin and myosin
Smooth Muscle
ability of smooth muscle to stretch without developing a lasting high tension
Plasticity
layers of connective tissue that encloses muscle and provide structure to th muscle as a whole and also compartmentalize the muscle fibers within the muscle
Mysia
sheath of dense fibrous connective tissue beneath the skin or around muscle fibers, holds muscle fibers together
Connective Tissue Coverings/Fascia
connective tissue surrounding the skeletal muscle
Epimysium
connective tissue that surrounds muscle fasicles
Perimysium
connective tissue that surrounds single muscle fibers
Endomysium
bundle of fibers
Fascicles
muscle cells that composes a fasciculus
Muscle Fiber
Skeletal muscle attachments:
T-A-T:
Tendon
Aponeuroses
Tendon Sheaths
attaches muscle to the periosteum of a bone
Tendon
flat layer ghin of sheets that attach to the coverings of a bone, another bone, or the skin
Aponeuroses
tubes of fibeous connective tissue that encloses certain tendons especial at the wrist and ankle
Tendon Sheathes
Attachment of bone ends of skeletal muscles:
Origin
Insertion
less movable, point of attachment, attachment of a muscle tendon to the stationary bone
Origin
more movable, distal to the movable bone
Insertion
Skeletal muscle shapes
PPCCF:
Parallel
Pennate (Uni, Bi, Multi)
Convergent
Circular
Fusiform
- fasciculi are parallel with the long axis of the muscle
- quadrilateral in shape
- examples: stylohyoid muscle
Parallel/Longitudinal
- fasciculi are short in relation to the entire length of the muscle
- obliquely toward the tendon like the plumes of a feather
Pennate
- arranged on only one side of the tendon
- example: extensor digitorium
Unipennate
- arranged on both sides of a centrally positioned tendon
- example: rectus femoris muscle
Bipennate
- have complex arrangement that involves convergence of several tendons
- example: deltoid muscle
Multipennate
- broad origin of fasciculi converges to a narrow, restricted insertion
- triangular in shape
- example: pectoralis major
Convergent
- arranged in circular pattern and enclose an orifice
- example: orbicularis oculi muscle
Circular
- nearly parallel with the longitudinal axis
- muscles tapers toward the tendons
- example: biceps brachii
Fusiform
elongated cylindrical cells that lie parallel to one another
Muscle fibers/Myofibers
Diameter and Length of Myofibers
Diameter: 10 to 100
Length: 30 or more
cell membrane of the muscle fiber
Sarcolemma
- cytoplasm of the muscle fiber
- multinucleated
- contains enzymes, sarcoplasmic reticulum, myofibrils
Sarcoplasm
- cytoplasm of the muscle fiber
- contains sarcoplasmic reticulum, enzymes, myofibrils
Sarcoplasm
- network of membrane enclosed tubules
- where protein and lipid are manufactured
- transport products
Sarcoplasmic reticulum
- extensions of sarcolemma
- perpendicularly to the sarcoplasmic reticulum
-runs transversely through the fiber
T-tubules/Transverse tubules
T tubules connect to the terminal cisterns of sarcoplasmic reticulum
Triad
- dilated sacs of sarcoplasmic reticulum
- ring like channels around myofibrils
Terminal cisterns
- simplest unit of muscle
- bundles of protein filaments
- cylindrical (1-2 um in diameter)
- consists to 2 kinds of myofilaments
myofibrils
- 6 nm in diameter
- composed of 3 kinds of proteins
Thin myofilaments/Actin
- 16 nm in diameter
- composed mainly of myosin (shaped like golf club)
Thick myofilaments/Myosin
Thin myofilaments 3 proteins:
Tropomyosin
Troponin
Actin
arranged in strands that are loosely attached to actin
Tropomyosin
located at regular intervals on the surgace of tropomyosin
Troponin
3 subunits of Troponin
I - binds with actin
C - binds with calcium
T - binds with tropomyosin
- attachment sites for myosin filaments
- double helix
- contains myosin binding-site that interacts with a cross bridge of a myosin molecule
Actin
basic structural and functional unit of a skeletal muscle
sarcomeres
- separate one sarcomere to the next
- network of protein fibers that forms a stationary anchor for actin myofilaments to attach
Z disk
each ___________ consists of two _________ bands separated by a __________ band
sarcomere
light-staining
dark-staining
- light staining bands
- consist of only actin myofilaments
I bands/Isotropic
- central dark-staining band
A band/Anisotropic
- center of A band that is a smaller’ lighter-staining region
H zone
- located at the center of H-zone
- consists of fine protein filaments that anchor the myosin filaments in place
M line
contain the actin-binding site and an ATP binding site
cross bridges
storehouse of the cell
mitochondria
- narrow zones that separate sarcomeres from one another
- contain thick myofilaments only
Z-line/Zuriachen
proteins that make up myofibrils
Myofilament
- bind to attachment sites
- bend and straighten
- break down ATP
Myosin heads
muscles that are primary concern with the movement
Prime movers/Agonist
- acts against prime movers
- working in reverse of that particular movement, preventing the prime mover to over extend
antagonists
- helps the prime movers by producing the same movement
synergists
- specialized synergists
- muscle which steadies the bone
- stabilize the origin of a prime mover
fixators
- neuron that stiimulates muscle contraction
- deliver stimulus to muscle tissue
Motor neuron
- refers to the axon terminal of a motor neuron together with the motor end plate
Neuromuscular junction/Myoneural junction
- the region of the sarcolemma adjacent to the axon terminal
Motor end plate
- expanded bulblike structures of the distal ends of the axon terminals
Synaptic end bulbs
- membrane enclosed sacs contained in synaptic end bulbs
- store chemicals called neurotransmitters including acetylcholine
Synaptic vesicles
- neurotransmitter released at neuromuscular junction in skeletal muscles
Acetylcholine
invaginate area of the sarcolemma under the axon terminal
synaptic gutter
space between the sarcolemma under the axon terminal
synaptic cleft
numerous folds of the sarcolemma along the synaptic gutter
subneural clefts
- composed of motor neuron together with all the muscle fibers it stimulates
- single motor neuron may innervate about 150 muscle fibers, depending on the region of the body
Motor unit
sliding of myofilaments and shortening of sarcomeres causes the shortening of the muscle fibers
Sliding Filament Theory
states that muscles either contract with all force possible under existing conditions or do not contract at all
All-or-None Principle
Phases of Contraction
Lag phase
Contraction phase
Relaxation phase
This principle states that when a motor unit receives a stimulus of sufficient intensity to bring forth a response, all the muscle fibers within the unit will contract at the same time, and to the maximum possible extent.
All-or-None Law