leptospirosis Flashcards

1
Q

leptopsirosis disebabkan oleh ?

A

spirochaeta dari genus leprospira

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2
Q

di daam tubuh hewan, leptosipra akan berkembang biak di ?

A

epitel tubulus ginjsl, dan mengalir melalui infiltrat uriin

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3
Q

lepstopirosis dikenal juga sebagai

A

weil’s disease

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4
Q

clinical hallmarks nya leptospirosis

A

jaundice, nephritis, splenomegaly

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5
Q

leptospirosis menginfeksi manusia melalui ?

A

mukosa / abrasi kulit, memasuki aliran darah dan berkembang biak

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6
Q

masa inkubasi leptospirosis ?

A

2-26 hari, rata rata 10 hari

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7
Q

bentuk berat dari leptospirosis adalah ?

A

well disease

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8
Q

tanda dan gejala well diseasee

A

jaundice, demam, gangguan ginjal, syok refrakter, perdarahn

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9
Q

demam pada leptospirosis bersifat ?

A

bifasik

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10
Q

diagnosis deginitif leptospirasis adalah ?

A

pemeriksaan langsung urin atau darah dengan mikroskop lapang gelap

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11
Q

pemeriksaan penunjang pada weil disease ditandai dengan ?

A

peningkatan blood urea nitrogen dan kreatinin serum, campuran hiperbilirubinemia terkonjugasi dan tak konjugasi, seta peningkatan aminotransferase dari 5 kali batas normal

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12
Q

test for diagnosis leptospirosis

A
  1. kultur
  2. MAT, meningkat 4 kalli
  3. ELISA/MAT
  4. PCR
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13
Q

sebutkan diagnosis bandingnya

A
  1. influenza
  2. malaria
  3. infeksi dengue, dll
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14
Q

tatalaksana nya

A
  1. suportif cairan
  2. antibiotik
    - doksisisklin, amoksisislin, azitromisisn oral (ringan)
    - penisilin G, doksisilin, ampisilin iv (sedang-berat)
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15
Q

untuk pekerja diberikan obat ?

A

doxycicline 200 mg, 1 wks 1

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