Leprosy Flashcards

1
Q

Dapsone MOA

A

Folic acid synthesis inhibition
Static

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2
Q

Dapsone kinetic

A

Hepatic metabolization
Urine clearance

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3
Q

Dapsone side effects

A
  1. GI
  2. Fever
  3. Rash
  4. G6PD hemolytic anemia
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4
Q

Clofazimine

A
  • Anti-inflammatory
  • Anti Leprosy MOA not known
  • GI edema
  • GI obstruction
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5
Q

Mycobacterium Avium Complex (MAC)

A
  • Clarithro, Azithro
  • Rifabutin
  • Macrolide + EMB
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