Lens Flashcards
What type of cataract is characteristic of ischemic ocular conditions?
Posterior subcapsular
Chronic UV radiation exposure typically causes what type of cataract?
Cortical
What are the most radiosensitive structures in the eye?
Lens > cornea > retina > optic nerve
How much radiation exposure leads to cataract formation? How long does it take to develop cataracts after radiation?
2 Gy in 1 fraction, 2-3 years
What lens capsule finding is seen when operating on patients with aniridia?
Thinner than normal lens capsule -> makes capsulorrhexis challenging
What is responsible for postoperative myopic shift?
Capsular contraction or phimosis
What complication is more common after intracapsular CEIOL than extracapsular?
Retinal detachment
What is posterior infusion syndrome or posterior fluid misdirection syndrome?
Occurs after hydrodissection -> fluid misdirected into vitreous cavity leading to anterior displacement of lens and shallowing of anterior chamber
Not associated with pain
What types of IOLs have been associated with highest rates of corneal decompensation?
Closed-loop ACIOLs, iris-clip lenses
Flexible/open-loop ACIOLs at less risk
What can be done to reduce increased risks of cataract surgery in patient with COPD?
Small-incision surgery: reduces risk of suprachoroidal hemorrhage and iris prolapse
Reverse Trendelenburg position may help patient breathe more easily
After performing LASIK in myopic patient, how will central corneal power differ when measured by keratometer versus topography?
Corneal curvature is overestimated by keratometry compared to topography (keratometry only measures central 3 mm)
What IOL is most likely to cause negative dysphotopsia?
Smaller square-edge PCIOL in the bag
What IOL pathology is associated with positive dysphotopsias?
Decentered PCIOLs
What carbohydrate metabolism change occurs in lens in presence of high levels of glucose?
Aldose reductase activity increases
What is the rate-limiting step in glucose phosphorylation in the lens? What occurs when glucose concentration increases in the lens?
Hexokinase reaction
Sorbitol pathway activated when glucose concentration increases -> aldose reductase is key enzyme in this pathway
What kind of patient would benefit from Trendelenburg positioning for cataract surgery?
Kyphotic patients