LEISHMANIA SPP.

Question 1

Live in mammalian macrophages as ____.

Answer 1

amastigotes

Question 2

How is it transmitted?

Answer 2

as promastigotes in sand flies

Question 3

describe the life cycle of Leishmania species

Answer 3

1) sand flies will take a blood meal and the promastigotes will infect the host
2) promastigotes are then ingested by macrophages and transform into amastigotes
3) sandfly takes a blood meal containing a parasitised cell ingesting the amastigotes
4) develop into promastigotes

Question 4

How different do promastigotes and amastigotes look?

Answer 4

PROMASTIGOTES have proper flagellum, which makes sense as they have to move

AMASTIGOTES are oval and more cell like

Question 5

What are the 2 potential consequences of Leishmaniasis?

Answer 5

1) CUTANEOUS
- skin macrophages

2) VISCERAL
- spleen/ liver/ marrow macrophages

Question 6

Cutaneous leishmaniasis symptoms

Answer 6

facial ulcers

Question 7

Visceral leishmaniasis symptoms

Answer 7

enlargement

Question 8

Majority of human parasites come from ___ reservoirs.

Answer 8

zoonotic

Question 9

L. _(a) is found in Africa and primarily favours (b) as hosts. It is a (c) form of Leismania.

Answer 9

a) aethiopia
b) rodents
c) cutaneous

Question 10

L. (a) is found all over, mainly (b) and is a form of (c) Leishmania

Answer 10

a) donovani
b) Europe
c) visceral