Leik hypertension Flashcards

1
Q

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NUMBER
2. Which of the following findings is most likely in young primigravidas with
pregnancyinduced hypertension?
A) Abdominal cramping and constipation
B) Edema of the face and the upper extremities
C) Shortness of breath
D) Dysuria and frequency

A
  1. B) Edema of the face and the upper extremities

Common signs and symptoms of
pregnancy-induced hypertension include edema of the face and the upper
extremities, weight gain, blurred vision, elevated blood pressure, proteinuria, and
headaches.

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2
Q
  1. A 75-year-old woman has been on nifedipine (Procardia XL) 10-mg capsule for many years to control her stage II hypertension. Her blood pressure at this visit is 165/80 mmHg. She is currently complaining of pain at her right hip and in both knees. She has increased her dose of ibuprofen (Motrin) from 400 mg three times daily (TID) to 800 mg TID. She is still in pain and would like something stronger.
    Which of the following statements is the best explanation of the effects of ibuprofen
    (Motrin) on her disease?
    A) It increases the chances of adverse effects to her health
    B) It inhibits the effect of renal prostaglandins and blunts the effectiveness of the diuretic
    C) It prolongs the therapeutic effects of hydrochlorothiazide and other diuretics
    D) None of the statements are true
A
  1. B) It inhibits the effect of renal prostaglandins and blunts the effectiveness of the diuretic

Nonsteroidal anti-inflammatory drugs (NSAIDs) and acetylsalicylic acid(ASA) inhibit the vasodilatory effects of prostaglandins, which predisposes the kidney to ischemia. NSAIDs can cause acute kidney injury by decreasing renal blood flow. Nonselective NSAIDs can adversely affect the kidneys, GI tract, liver, cardiovascular
system, and the lungs (bronchospasm).

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3
Q
  1. A 63-year-old patient with a 10-year history of poorly controlled hypertension
    presents with a cluster of physical exam findings. Which of the following
    clusters indicates the target organ damage commonly seen in hypertensive patients?
    A) Pedal edema, hepatomegaly, and enlarged kidneys
    B) Arteriovenous (AV) nicking, left ventricular hypertrophy, and stroke
    C) Renal infection, S3 heart sound, neuromuscular abnormalities
    D) Glaucoma, jugular vein atrophy, heart failure
    616
A
  1. B) Arteriovenous (AV) nicking, left ventricular hypertrophy, and stroke

AV nicking and copper wire/silver wire arterioles are signs of hypertensive retinopathy, left ventricular hypertrophy affects the heart, and stroke damages the
brain. These are all examples of target organ damage.
1341

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4
Q
49. All of the following are possible causes for secondary hypertension except:
A) Acute pyelonephritis
B) Pheochromocytoma
C) Renovascular stenosis
D) Coarctation of the aorta
640
A
  1. A) Acute pyelonephritis

Acute pyelonephritis does not involve any vascular
change; however, chronic pyelonephritis (reflux nephropathy) is a factor for secondary
hypertension. Pheochromocytoma is a rare tumor of the adrenal glands that results in
a release of too much epinephrine and norepinephrine, hormones that control heart
rate, metabolism, and blood pressure. Renovascular stenosis is a narrowing of one or
both arteries leading to the kidneys. It can cause severe hypertension and irreversible
kidney damage. Coarctation of the aorta is a congenital heart defect of the aorta; it is
a narrowing of the aorta that causes the heart to work harder to get blood to flow
through the narrow aortic passageway to other organs, which, in turn, causes an
increase in blood pressure.
1365

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5
Q
  1. You note the following result on a routine urinalysis of a 37-year-old primigravida
    who is at 30 weeks gestation. Leukocyte = trace, nitrite = negative, protein = 2+,
    blood = negative. Her weight has increased by 5 lbs during the past week. Which of
    the following is most likely?
    A) HELLP syndrome
    B) Pregnancy-induced hypertension (preeclampsia)
    C) Eclampsia of pregnancy
    D) Primary hypertension
A
  1. B) Pregnancy-induced hypertension (preeclampsia) This patient is manifesting
    the classic triad of symptoms of preeclampsia: hypertension, edema (weight gain),
    and proteinuria.
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6
Q
225. What is the most common cause of left ventricular hypertrophy in the United
States?
A) Chronic atrial fibrillation
B) Chronic hypertension
C) Mitral valve prolapse
D) Pulmonary hypertension
A
  1. B) Chronic hypertension

Left ventricular hypertrophy develops in response to
some factor, such as high blood pressure, that requires the left ventricle to work
harder. As the workload increases, the walls of the chamber grow thicker, lose
elasticity, and eventually may fail to pump with as much force as a healthy heart.
High blood pressure, a blood pressure reading greater than 140/90 mmHg, is the
greatest risk factor.
1541

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7
Q
  1. A 55-year-old woman with a history of migraine headaches has recently been
    diagnosed with stage II hypertension. Her EKG strips reveal second-degree heart
    block. The chest x-ray is normal. Which of the following drugs should this patient
    avoid?
    A) Angiotensin-converting enzyme (ACE) inhibitors
    B) Angiotensin receptor blockers
    C) Diuretics
    D) Calcium channel blockers
A
  1. D) Calcium channel blockers

Common side effects of calcium channel blockers
include headaches, edema of the lower extremities, and heart block or bradycardia.
Contraindications for calcium channel blockers include second- or third-degree
atrioventricular (AV) block, bradycardia, and congestive heart failure.

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8
Q
  1. Lifestyle modifications are an important aspect in the treatment of hypertension. Which of the following statements is incorrect?
    A) Reduce intake of sodium, potassium, and calcium
    B) Reduce intake of sodium and saturated fats
    C) Exercise at least three to four times per week
    D) Maintain an adequate intake of potassium, magnesium, and calcium
A
  1. A) Reduce intake of sodium, potassium, and calcium

Lifestyle modifications
for hypertension include exercise three to four times a week, diet modifications of reduced intake of sodium and saturated fats, and adequate dietary intake of
potassium, magnesium, and calcium.
1641

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9
Q
  1. Which of the following classes of antihypertensive drugs should a patient be
    weaned off slowly to avoid the risk of severe rebound hypertension?
    A) Diuretics
    B) Beta-blockers
    C) ACE inhibitors
    D) Calcium channel blockers
A
  1. B) Beta-blockers

Reverse rebound hypertension can occur if beta-blockers are abruptly stopped. Recommendations include weaning off the beta-blockers
when changing medications.
1642

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10
Q
  1. All of the following are clinical eye findings found in some patients with chronic
    uncontrolled hypertension. Which is not associated with this disorder?
    A) AV nicking
    B) Copper wire arterioles
    C) Flame-shaped hemorrhages
    D) Microaneurysms
A
  1. D) Microaneurysms

Keith Wagener Barker (KWB) grades for uncontrolled
hypertension are as follows: Grade 1—generalized arteriolar constriction seen as
“silver wiring” and vascular tortuousities; grade 2—grade 1 plus irregularly located,
tight constrictions known as AV nicking or AV nipping; grade 3—grade 2 plus cotton
wool spots and flame-shaped hemorrhages; and grade 4—grade 3, but with swelling
of the optic disc (papilledema). Microaneurysms occur with diabetic retinopathy.

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11
Q
  1. A 40-year-old Black man with asthma and hypertension has been following a
    lowfat, low-sodium diet and walking three times a week for the past 6 months.
    His blood pressure readings from the past two visits were 160/95 and 170/100
    mmHg. On this visit, it is 160/90. What is the most appropriate action for the nurse
    practitioner to follow at this visit?
    A) Continue the lifestyle modifications and recheck his blood pressure again in 4
    weeks
    B) Initiate a prescription of hydrochlorothiazide 12.5 mg PO daily
    C) Initiate a prescription of atenolol (Tenormin) 25 mg PO daily
    D) Refer the patient to a cardiologist for a stress EKG
    935
A
  1. B) Initiate a prescription of hydrochlorothiazide 12.5 mg PO daily

The Eighth Joint National Committee (JNC 8)-recommended pharmacological
treatment for Black adult hypertensive patients (without chronic kidney disease or
diabetes) is a thiazide-type diuretic or calcium channel blocker (CCB), used alone or
in combination.

For White adults, the JNC 8 recommends a thiazide-type diuretic or angiotensin-converting enzyme (ACE) inhibitor or an angiotensin receptor blocker (ARB) or a CCB, used alone or in combination. Do not combine an ACE inhibitor with an ARB.

Although unusual, a serious adverse effect from these two drug classes is angioedema. Beta-blockers should be avoided in patients with chronic lung disease, such as asthma and chronic obstructive pulmonary disease (COPD), because they can cause bronchoconstriction.
1660

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12
Q
  1. Terazosin (Hytrin), an alpha-blocker, is used to treat which of the following
    conditions?
    A) Benign prostatic hypertrophy and hypertension
    B) Chronic prostatitis and atrial fibrillation
    C) Urinary tract infections and arrhythmias
    D) Benign prostatic hypertrophy and chronic prostatitis
    949
A
  1. A) Benign prostatic hypertrophy (BPH) and hypertension

Terazosin (Hytrin)
is a treatment option for men with BPH and hypertension. Symptoms of BPH
include difficulty urinating (hesitation, dribbling, weak stream, and incomplete
bladder emptying), painful urination, and urinary frequency and urgency. Terazosin
is in a class of medications called alpha-blockers. It relieves the symptoms of BPH by
relaxing the muscles of the bladder and prostate. It lowers blood pressure by relaxing
the blood vessels so that blood can flow more easily through the body.

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13
Q
  1. A nurse practitioner is taking part in a community outreach program for a local
    hospital. Most of her audience has a diagnosis of hypertension. They are all
    interested in learning more about a proper diet. When discussing potential sources of
    potassium and magnesium, which of the following are the best sources for these two
    minerals?
    A) Fruits, leafy greens, and nuts
    B) Whole grains, red meat, and dairy
    C) Bananas, beef, and yogurt
    D) Mushrooms, fermented foods, and vegetables
    974
A
  1. A) Fruits, leafy greens, and nuts

The best sources of both potassium and
magnesium are fruits (bananas, cantaloupe, papaya, kiwi), leafy greens (spinach, kale,
chard), and nuts (cashews, almonds, walnuts, peanuts).
1699

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14
Q
  1. Which of the following conditions are possible causes of secondary hypertension?
    A) Leukemia and thalassemia major
    B) Hashimoto’s thyroiditis and polycystic ovaries
    C) Renal stenosis and adrenal tumors
    D) Myocardial infarction and coronary artery disease
A
  1. C) Renal stenosis and adrenal tumors

Secondary hypertension is most likely
seen following renal stenosis and adrenal tumors. Renal stenosis causes secondary
hypertension by plaque formation in the arteries, causing damage to coronary arteries
(atherosclerosis). Adrenal tumors initiate secondary hypertension by releasing a large
amount of aldosterone, which causes water and salt retention and loss of too much
potassium.
1759

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15
Q
  1. All of the following drug classes are approved for treating hypertension. Which of
    the following antihypertensive drug classes is associated with the largest number of
    research studies?
    A) Angiotensin-converting enzyme (ACE) inhibitors
    B) Angiotensin receptor blockers (ARBs)
    C) Thiazide diuretics
    D) Calcium channel blockers (CCBs)
A
  1. C) Thiazide diuretics

Thiazide diuretics have been used to treat hypertension for
many decades and numerous placebo-controlled studies have documented their
effectiveness as antihypertensive drugs.

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16
Q
  1. An elderly Hmong patient, who is originally from Thailand, is seen by the nurse
    practitioner for a follow-up visit. He is accompanied by his eldest daughter. The
    patient presented 6 weeks ago with complaints of the recent onset of morning
    headaches. He was diagnosed with stage 2 hypertension and prescribed
    hydrochlorothiazide, one 25-mg tablet daily. On this visit, he tells the nurse
    practitioner that the new medicine cured the headache, so he stopped taking it.
    What is the best plan to follow during this visit?
    A) Educate the patient about hypertension, how the medicine works on his body,
    and the importance of taking his pill daily
    B) Reassure the patient that he can resume his prescription medicine again the next
    morning
    C) Tell the patient that you will lower the dosage of hydrochlorothiazide to 12.5
    mg daily
    D) Speak to the patient in a loud voice and confront him about his behavior
A
  1. A) Educate the patient about hypertension, how the medicine works on his body, and the importance of taking his pill daily

When Hmong (an ethnic group
prevalent in Thailand, Myanmar, Laos, and Vietnam) see a medical doctor for a symptom, they expect to be treated and “cured” of their illness after one visit. When
the symptoms disappear, many will stop taking the medicine. When medication is to
be taken on a long-term basis, it is important to educate the patient (and the
patient’s family) about the disease (in this case, hypertension), how the medicine
works on the body, and the reason why the patient has to take the medicine as
prescribed (in this case, daily). Many Southeast Asians are very polite and consider
speaking in a loud voice, staring, or confrontation to be rude behavior.
1894

17
Q
  1. A 90-year-old woman is diagnosed with isolated systolic hypertension of the
    elderly. Which of the following antihypertensive medications are preferred for
    the treatment of this condition?
    A) Calcium channel blockers and thiazide diuretics
    B) Angiotensin-converting enzyme inhibitors and loop diuretics
    C) Beta-blockers and potassium-sparing diuretics
    D) Alpha-blockers and calcium channel blockers
A
  1. A) Calcium channel blockers and thiazide diuretics

Calcium channel blockers
(CCBs) and thiazide diuretics are preferred for treatment of isolated systolic
hypertension of the elderly. There is no preference of one over the other, and therapy
may be started with either a thiazide diuretic or a CCB. Isolated systolic
hypertension of the elderly is caused by hardening of the arteries, resulting in
increased peripheral vascular resistance. The goal for patients aged 60 years or older
is blood pressure less than 150/90 mmHg unless diabetic or they have chronic
kidney disease (goal BP <140/90 mmHg). Watch for orthostatic hypotension (or
decrease in systolic blood pressure of >20 mmHg), which is a risk factor for falls.
2005