Leg Ulceration Flashcards
What are the classifications of leg ulcers?
- Ischaemic/arterial insufficiency aka peripheral arterial disease
- Neuropathic
- Stasis/venous
Other:
- Infective: syphilis, myco, osteomyelitis
- Neoplastic: SCC, BCC, melanoma, Kaposi’s sarcoma
- Systemic: pyoderma gangrenosum
- Traumatic: thermal burns, bites, radiation
Causes of neuropathic leg ulcers
- DM
- EtOH
- Spinal cord lesions
- Tabes dorsalis: untreated syphillis infection can lead to slow demylination of the dorsal column nerves
- Syringomyelia: cyst forms within on spinal cord
Hx of ischaemic ulcers
Hx:
- V. painful
- Hx of claudication
- CV risk factors
- Previous peripheral vascular surgery
Describe how an ischaemic ulcer appears on inspection
- Location: distal periphery, over dorsum of foot or pretibia
- Punch-out edges
- Ulcer base => poorly developed gray granulation tissue
- Surrounding skin is pale or mottled with no signs of inflammation
- Little bleeding when debrided
Hx of neuropathic ulcers
- Painless
- Hx of Dm or other causes of neuropathy (DM, EtOH, spinal cord lesions, syringomyelia, tabes dorsalis
Describe how an neuropathic ulcer appears on inspection
- Deep
- Location:
a. pressure points or calluses
b. plantar surface of MTP joints
c. “Bunion” or “bunionette” areas
d. Dorsum of IP joints
e. Base of 5th MT
f. MM or LM
g. Callused posterior rim of heel pad - features of distorted foot architecture:
a. Hyperextension of MTP joints
b. Hyperflexion of IP joints
c. Charcot’s deformity
List signs of neuropathy
- Hypoaesthesia
- proprioception
- 2-point discrimination
- Vibratory perception
Hx of venous ulcers
- Hx of venous insufficiency: varicose veins, superfiicla thrombophlebitis or DVT, variceal bleeding
- Previous venous surgery
Describe how an venous ulcer appears on inspection
- Larger and irregular edge
- Shallow
- Location: over gaiter area (commonly medial malleolus)
- Moist granulating base
- Surrounded by zone of inflammation and stasis dermatitis
What are the associated signs of venous insufficiency (if suspecting venous ulcer)?
- varicose veins
- pitting oedema
- varicose eczema
- Pigmentation
- Lipodermatosclerosis (champagne leg)
- Atrophie blanche (white stellate scars)
Compare the ulcers (arterial, venous, neuropathic) in SITE
- Arterial
distal at toe tips
Pressure areas - Venous
gaiter area
3. Neuropathic dorsum of PIP / DIP Plantar surface MTP MM or LM Heel Other calloused areas
Compare the ulcers (arterial, venous, neuropathic) in SIZE/SHAPE/DEPTH
- Arterial
small deep - Venous
Large, irregular, shallow - Neuropathic
Variable
Compare the ulcers (arterial, venous, neuropathic) in BASE
- Arterial
pale and sloughy - Venous
granulating - Neuropathic
granulating
Compare the ulcers (arterial, venous, neuropathic) in EDGES
- Arterial
punched out - Venous
sloping and shallow - Neuropathic
punched out
Ix of leg ulcers
- FBE / U&E / CRP / glu / HbA1C / vasculitic screen / ESR / thrombophilic screen
- Swab m/c/s
- Xray ± bone scan ± MRI
- Duplex (arterial or venous)
- CTA
- DSA
- Biopsy