Leg Ulcer Flashcards

1
Q

List a differential diagnosis of leg ulcers.

A
Venous ulcers 
Mixed ulcers 
Arterial ulcers 
Neuropathic ulcers 
Pressure ulcers 
Lymphoedema ulcers 
Traumatic ulcers
Vasculitic ulcers 
Marjolin’s ulcers
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2
Q

What type are the majority of leg ulcers?

A

Venous ulcers – 70%

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3
Q

List two key features of the ulcer history.

A

Is the ulcer painful?

How long has the ulcer been there?

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4
Q

What is a Marjolin’s ulcer?

A

A squamous cell carcinoma arising from chronically inflamed tissue

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5
Q
How does the pain differ in:
Venous Ulcers
Arterial Ulcers
Neuropathic Ulcers
Pressure Ulcers
A
- Venous Ulcers
Not particularly painful 
Pain is relieved when the leg is elevated (because pain/ulcer is caused by venous stasis)
- Arterial Ulcers
Quite painful 
Pain is worse when the leg is elevated (because pain is due to ischaemia) 
- Neuropathic Ulcers 
NO pain
- Pressure Ulcers
Exquisitely tender
Not necessarily painful
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6
Q
How does the time of presentation of ulcers differ in:
Venous Ulcers
Arterial Ulcers
Neuropathic Ulcers
Pressure Ulcers
Marjolin Ulcers
A
  • Venous Ulcers
    Present late because they aren’t that painful
    Tend to have long, recurring history
  • Arterial Ulcers
    Present early because they are painful
    Often present secondary to trivial trauma
  • Neuropathic Ulcers
    Present late because they are not painful
  • Pressure Ulcers
    Can develop surprisingly fast (especially in hospital because of bed rest)
  • Marjolin Ulcers
    Long-history of an ulcer/chronic skin inflammation that has suddenly changed
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7
Q

List some key associated features of:
Venous Ulcers
Arterial Ulcers
Neuropathic Ulcers

A
  • Venous Ulcers
    Varicose veins
    Skin changes: haemosiderin deposition, stasis dermatitis, lipodermatosclerosis
    Ankle oedema
  • Arterial Ulcers
    Peripheral vascular disease (e.g. claudication, night pain, rest pain)
    Coronary artery disease (e.g. angina, SOBOE)
    Cerebrovascular disease (e.g. stroke, TIA)
  • Neuropathic Ulcers
    Sensory loss
    Unstable gait
    Infected ulcers (mainly in diabetics)
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8
Q
List risk factors for:
Venous Ulcers
Arterial Ulcers
Neuropathic Ulcers
Pressure Ulcers
A
- Venous Ulcers
Presence of varicose veins 
Immobility
Malnourishment 
Recurrent DVTs 
Pelvic mass compressing iliac veins 
AV malformations 
Major joint replacement (carries high subclinical DVT risk)
- Arterial Ulcers
Atherosclerosis risk factors: hypertension, diabetes, smoking, hypercholesterolaemia etc.
- Neuropathic Ulcers
Diabetes mellitus 
Alcohol abuse 
- Pressure Ulcers
Long-term bed rest/ long lie
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9
Q
Describe the common sites of the following types of ulcer:
Venous Ulcers
Arterial Ulcers
Neuropathic Ulcers
Pressure Ulcers
A
  • Venous Ulcers
    Gaiter area of the legs (mainly above the medial malleolus)
    This is where venous pressure is highest
  • Arterial Ulcers
    Distal areas (e.g. between the toes) and frequently compressed areas (e.g. ball of foot)
  • Neuropathic Ulcers
    Pressure areas (e.g. ball of foot) – because it is subject to repetitive trauma
  • Pressure Ulcers
    Bony prominences that experience constant pressure (e.g. heel)
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10
Q

Describe the characteristics of:
Venous Ulcers
Arterial Ulcers
Neuropathic Ulcers

A
- Venous Ulcers
Shallow 
Wet 
Irregular borders that look white and fragile 
- Arterial Ulcers
Deep
Dry 
Punched-out appearance 
Often elliptical
- Neuropathic Ulcers
Thick, keratinized raised edges surrounding the ulcer
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11
Q

Which diseases are associated with pyoderma gangrenosum?

A
Inflammatory bowel disease 
Blood dyscrasias (e.g. multiple myeloma)
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12
Q

Describe the typical appearance of pyoderma gangrenosum.

A

An ulcer with a characteristic purple halo around it

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13
Q

Venous ulcers can scar leading to white patches of scarred skin. What is this feature called?

A

Atrophie blanche

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14
Q

What is the term used to describe severe lipodermatosclerosis?

A

Inverted champagne bottle sign

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15
Q

Describe some features of the affected limb in a patient with arterial ulcers.

A
Cold 
Pale
Absent/weak pulses 
Delayed capillary refill time 
Atrophic skin changes (dry, shiny, hairless)
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16
Q

What is Buerger’s test? Describe how it is performed and what a positive result indicates.

A

Whilst the patient is supine, raise the leg up until it goes pale
NOTE: in normal people, the leg should remain pink even at 90 degrees
The angle at which it goes pale is ‘Buerger’s angle’
Then the leg is put back down
With positive Buerger’s sign – the leg will slowly turn pink but then it will go red (this is due to reactive hyperaemia)

17
Q

Describe some features of the affected limb in a patient with neuropathic ulcers.

A
Loss of sensation (gloves and stockings distribution)
Foot deformities (e.g. Charcot foot)
18
Q

Why would you check FBC in a patient with ulcers?

A

Anaemia could worsen the ischaemia that causes ulcers

19
Q

List some other investigations that you would use in a patient with a suspected venous ulcer.

A
Fasting lipids 
Capillary glucose 
Urinalysis 
Venous duplex ultrasound – good for assessing saphenofemoral competence
ABPI
20
Q

Why is it important to calculate the ankle-brachial pressure index (ABPI) before treating an ulcer?

A

This allows assessment of arterial disease

ABPI < 0.8 – do NOT apply pressure bandage because it will worsen the ischaemia

21
Q

Which ulcers may require a biopsy?

A

Marjolin’s ulcer

22
Q

Outline the management of venous ulcers.

A
Adequate nutrition
Leg elevation 
Compression bandages
Elastic stockings 
Varicose vein surgery
23
Q

Define critical limb ischaemia.

A

Severe obstruction of the arteries which markedly reduces blood flow to the extremities and has progressed to the point of causing severe pain, ulcers or gangrene. These patients will have rest pain.

24
Q

List some investigations for suspected arterial ulcers.

A
Duplex ultrasonography – assess arterial patency
Percutaneous angiography 
ECG 
Fasting lipids, glucose, HbA1c
FBC
25
Q

Outline the management of arterial ulcers.

A

Dress the ulcer to prevent infection
Analgesia
Antibiotics (if signs of infection)

26
Q

List some surgical options for treating arterial ulcers.

A

Angioplasty
Bypass surgery
Amputation

27
Q

What causes acute limb ischaemia?

A

A sudden lack of blood flow to a limb

28
Q

What are the signs of acute limb ischaemia?

A
6 Ps of acute limb ischaemia: 
Pale 
Pulseless 
Painful
Paralysis 
Paraesthesia
Perishingly cold
29
Q

List some possible interventions for acute limb ischaemia.

A
Embolectomy 
Percutaneous thrombolysis 
Revascularisation angioplasty
Bypass surgery
Amputation
30
Q

Outline the treatment of neuropathic ulcers.

A

Foot care
Manage diabetes
Debridement of necrotic tissue
Treat infections

31
Q

What is a major complication of neuropathic ulcers?

A

Osteomyelitis

32
Q

Outline the management of pressure ulcers.

A

Record the ulcer
Relieve the ulcer
Reduce further ulcers
Reassess ulcer

33
Q

List some surgical options for varicose veins.

A

Avulsion/phlebectomy
Stripping
Injection sclerotherapy
Radiofrequency ablation