Leffler 1.1

Question 1

Drugs that affect uterine function:

Answer 1

• Tocoloytic
  
  • aka relaxants
  • suppresses uterine contractoins
  • use: Suppress preterm labor
• Oxytocic
  
  • aka stimulants
  • stimulates uterine contractions
  • uses:
    
    • induction of labor
    • induction of abortion
    • control postpartum bleeding

Question 2

Tocolytic Drugs

Answer 2

• Magneisum Sulfate
• Nifedipine
• Terbutaline
• Indomethacin

Question 3

Oxytocic Drug names

Answer 3

• Oxytocin
• Ergonovine & methylergonovine
• Carboprost tromethamine

Question 4

Drugs that promote cervical ripening

Answer 4

• Prostaglandins
• Drugs:
  
  • Dinoprostone
  • Misoprostol
• Used with oxytocin to induce labor

Question 5

Drugs that affect labor

Answer 5

Question 6

Drugs for Emergency Contraception

Answer 6

• Regular combination oral contraceptive
  
  • estrogen (ethinyl estradiol) + progestin (Levoorgestrel)
• high dose progestin only (Levonorgestrel)
  
  • Plan B One-Step
  • Plan B
  • Next Choice
• Ulipristal Acetate

Question 7

Drugs for Abortion

Answer 7

• Mifepristone
• Prostanglandins
  
  • misoprostol
  • carboprost
  • dinoprostone

Question 8

Mifepristone

Answer 8

• Synthetic steroid
• blocks progesterone and glucocorticoid receptors
• causes detachment of blastocyte via decreased endometrial blood supply
• Only indication:
  
  • termination of early intrauterine pregnancy
• Coadministered w/ misoprostol
• 95% effective
• side effects:
  
  • abdominal pain
  • abdominal bleeding
• used in both early and 2nd trimester termination