Lecure 4 Flashcards

Cell Physiology III & Basic Biochem

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1
Q

What cells are important for controlling transport

A

Epithelial Cells

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2
Q

Properties of Epithelial cells

A

have asymmetrically distributed transporters, are interlinked by protein linkages, have high level of cell type diversity, abundant mitochondria

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3
Q

how do tight epithelia transfer solutes across the cell?

A

Tight epithelia can transfer solutes across the cell using transporters on the apical and basolateral plasma membrane

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4
Q

how do Leaky epithelia move solutes

A

in leaky epithelia small solutes can also move between cells by passing through the tight junctions that interconnect cells

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5
Q

where is energy stored

A

in electrochemical gradients, diffusion gradients are a form of energy storage, can either be chemical gradient or electrical gradient or both

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6
Q

What controls the relative charges of membranes and gradients?

A

the movement of ions

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7
Q

What is the role of enzymes?

A

Enzymes (catalysts) reduce activation energy

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8
Q

What are Carbohydrates?

A

Polymers made of monosaccharides, which are joined by glycosidic bonds

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9
Q

What are Polysaccharides?

A

Polysaccharides are polymers of monosaccharides. They are combined in a linear fashion and may contain additional amino sugars

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10
Q

What is Gluconeogenesis?

A

input of an amino acid, pyruvate or small lipid and you get the output of glucose of glycogen

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11
Q

Glycolysis

A

Start with glucose and get out 2 pyruvate

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12
Q

Where does glycolysis

A

Occurs in the cytoplasm

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13
Q

What are lipids?

A

highly non- polar, Glycerol and up to three fatty acids

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14
Q

what are fatty acids?

A

long chains of hydrocarbons

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15
Q

Poly unsaturated lipid

A

more than one double bond

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16
Q

mono unsaturated lipid

A

one double bond

17
Q

saturated lipid

A

no double bonds

18
Q

Process of Fatty Acid Oxidation

A

Fatty acids are broken down to produce acetyl-CoA, each pair of carbons in the FA chain are used to produce 1 acetyl-CoA

19
Q

How can Acetyl CoA be produced?

A

Pyruvate, Amino acids (protiens), fatty acids, ketone bodies, lactic acid

20
Q

Apical side of epithelial cells

A

Outside of the cell have cillia or microcillia

21
Q

Basolateral side of of epithelial cells

A

inside of the cell

22
Q

Simple Squamous Epithelium

A

Flat cells, Allows material to pass through by diffusion and filtrations, secretes substances for lubricating (mucus) things can’t diffuse across dry membranes

23
Q

Where are simple squamous epithelium found

A

Air sacs of lungs and the lining of the heart, blood vessels and lymphatic vessels

24
Q

Simple cuboidal epithelium

A

secretes and absorbes, takes longer for molecules to diffuse through than the simple squamous. located in the ducts and secretory portions of small glands and in kidney tubules

25
Q

Simple Columnar epithelium

A

absorbs things and also secrete mucous and enzymes. Located in the bronchi, uterus and digestive tract, bladder

26
Q

Stratified Squamous Epithelium

A

lines the esophagus, mouth and vagina, protects against abrasion

27
Q

Which of the following organs might be composed of many epithelial cells?
a. Kidneys
b. Lungs
c. Skin
d. Small intestine
e. all the above

A

all the above and more!

28
Q

Types of energy

A

Radiant, mechanical, electrical, thermal, chemical

29
Q

Lactase is the enzyme found in the small intestine which breaks the disaccharide lactose into the hexoses galactose and glucose. Most people stop reduce lactase production with age. Treatment of lactose intolerance is often through exogenous lactose. What does this do?
a. Increase the speed of the reaction
b. Decreases the breakdown of lactose into glucose and galactose
c. reduced the energy required to start the lactase mediated reaction
d. causes the breakdown of lactose

A

C. reduced the energy required to start the lactase mediated reaction

30
Q

Common energy carrying molecules

A

ATP, ADP, GTP, PCr

31
Q

what do common energy carrying molecules often involve

A

phosphate bonds

32
Q

What do chaperones do for proteins

A

help proteins fold correctly. Heat shock proteins (Hsp) help to maintain or refold proteins