Lectures for exam 1 Flashcards
Define Automaticity
Poduce impulse without stimulation
Which cells exhibit Automaticity?
Pacemaker cells in SA node
Define Excitability
Ability to respond to an electrical stimulus
Which cells exhibit Excitability?
Electrical conduction cells (myocardial cells)
Define Conductivity
Ability to transmit electrical signal from cell to cell
Which cells exhibit Conductivity?
Electrical conducting cells (myocardial cells)
3 cells of the heart?
- Electrical conducting cells
- Myocardial cells
- Pacemaker cells
Which cells are the hard wiring of the heart?
Electrical conducting cells
Which cells are the contractile machinery of the heart?
Myocardial cells
Which cells are the muscle cells of the atria and ventricles?
Myocardial cells
Which cells are able to depolarize spontaneously and are the normal electrical power source?
Pacemaker cells
What determines the rate of the pacemaker cells? (2 things)
- Innate electrical characteristics of cells
2. External neurochemical input
Examples of electrical conducting cells?
AV Node, His bubdle, LBB, RBB, Ant and Post Fascicles, Purkinge fibers
Pathway of electricity in the heart to myocardial cells?
Pacemaker->Contracting pathway->myocardial cells
What is the Cardiomyocyte Action Potential responsible for initiating?
Initiating each cardiac contraction
What initiates cardiac contraction?
Cardiomyocyte Action Potential
What are the 2 types of Cardiomyocyte Action Potential?
Spontaneous and Non-spontaneous
Are pacemaker cells in the SA node spontaneous or non-spontaneous Cardiomyocyte Action Potential?
Spontaneous
Are cardiac muscle cells spontaneous or non-spontaneous Cardiomyocyte Action Potential?
Non-spontaneous
What chemicals increases rate of pacemaker cell discharge causing increased heart rate?
Catecholamines (Epi and Norepi)
What chemical causes the decrease of pacemaker cell discharge thus slowing the heart rate?
Acetylcholine
What releases Acetylcholine?
Released during vagal stimulation
What causes myocardial cells to contract?
Depolarization which releases calcium from sacroplasmic reticulum
What type of coupling do myocardial cells exhibit?
Excitation-contraction coupling
What muscle components do myocardial cells contain?
Actin and myosin
What does the EKG waveform primarily reflect?
Electrical activity of myocardial cells
What are the 3 main characteristics of the EKG waveform?
- Duration in ms
- Amplitude in mV
- Configuration
When does ventricular excitation begin?
Begins at atrial relaxation
Time duration of small square on EKG paper?
0.04sec
Time duration of large square on EKG paper?
0.20 sec
How many small squares make up a large square on EKG paper?
5 small squares long and high
How many precordial leads are there?
Six
Precordial leads aka?
Chest leads or V leads
Which are the six precordial leads?
V1-V6
How many Limb Leads are there?
Three
What are the three Limb Leads called?
Lead 1
Lead 2
Lead 3