Lecture: Mental Disorders

Question 1

What are two genes involved in bipolar disorder?

Answer 1

• CACNA1C:
  Chromosome 12, hippocampus and acc impaired, calcium channel.
• ANK3:
  Chromosome 10, sodium and potassium channel protein.

Question 2

What gene is disrupted in schizophrenia 1?

Answer 2

• DISC1

Question 3

What can be concluded from the concordance rate?

Answer 3

It is the presence of the trait in monozygotic twins, if it is 100 the trait is purely genetic. Otherwise it is multifactorial.

Question 4

What is the effect of changing DSM-5 or ICD?

Answer 4

Classification of mental disorders is different, which can impact medical costs or stigma.