Lecture IV: Vector Borne Apicomplexans

Question 1

Babesia microti location

Answer 1

only RBCs

Question 2

deinitive host of babesia microti

Answer 2

deer tick

Question 3

Where is babesia microti

Answer 3

in the NOrtheast and upper midwest

Question 4

What has the maltese cross

Answer 4

babesia microti

Question 5

Malaria organis

Answer 5

P.falciparum or vivax or kownlesi or ovale or malariae

Question 6

Whats significant about transmission of babesia microti

Answer 6

it requirs two tick bites… the tick spits in sporozoites that devo to gametes–> then tick will redeliver and pick up laters

Question 7

Malaria causes death moslty in :

Answer 7

children and prima gravida females

Question 8

Most morbidity of Plasmodium is by:

Answer 8

plasmodium falciparum

Question 9

Plasmodiums or malaria infects

Answer 9

hepatocytes or erhythrocytes

Question 10

hot spots for malaria

Answer 10

arfica, brazil and some in south america

Question 11

P. falciparum distribution

Answer 11

global; lots in africa and western pacific and SE asia and S america

Question 12

P.falciparum relapses from liver form?

Answer 12

no

Question 13

P. vivax distribution

Answer 13

most in asia ans S america

Question 14

does P. Vivax have a relase from liver form

Answer 14

yes

Question 15

P.vivax and P ovale fever cycle burst

Answer 15

48 hrs

Question 16

P. malaria fever cycle burst

Answer 16

72 hrs spike

Question 17

P, falicparum fever cycle burst

Answer 17

48 hrs spike

Question 18

Extereme cerebral malaria results in only this type of malaria:

Answer 18

P. falicparum

Question 19

these two forms of plasmodium (malaria) result in hepatic forms

Answer 19

P. vivax and P. ovale

Question 20

how does malaria escape immune ssytem

Answer 20

switches out the antigens it expresses every few waves

Question 21

an unarousable coma not due to any other causes is

Answer 21

cerebral malaria

Question 22

cerebral malasia caused by P. falcipurm is seen in kids at what age:

Answer 22

over 2

Question 23

Acute respiratory distress can occur:

Answer 23

quickly in malaria

Question 24

anemia caused by what forms of plasmodium

Answer 24

falciparum and vivax

Question 25

this will have multiple rings per RBC on staining

Answer 25

P. falcipurum

Question 26

this will have engagement ring in the RBC

Answer 26

P. malaria

Question 27

people became susupetible to malaria bc

Answer 27

anti-malaria resistance drugs adn insecticides

Question 28

drug resistance to malaria occrured bc

Answer 28

misuse of anti-malarials

people only using single dose verse combination therapy

Question 29

tips for abroad to prevent malaria

Answer 29

bed nets, avoid mosquitos, RTS vaccine

Question 30

natural malaria infections:

Answer 30

malaria endemic area–> children infected early and build resistance d/t exposure but is incomplete
pregant women lose resistance to infection in 1st preggers

Question 31

Methods for vector control

Answer 31

2 blood meals
barriers
release of sterile mosquitos
release bio-engineerd mosquitoes

Question 32

pt comes in with rapid breathing and confusion.. which plasmodioum

Answer 32

P.falciparum

Question 33

Can you develop lifelong immunity to malaria?

Answer 33

no, you can quickly devo tolerance but this wanes quickly if you leave area with the exposures