Lecture Exam 2 Flashcards
Who was Matthias Schlieden
He was a botanist
Who was Theodor Schwann?
He was a zoologist
What are the 3 main characteristics of a cell?
- They are the building blocks for all living things
- It is the unit of structure, physiology, and organization in living things
- It retains a dual existence as distinct entity and building block of organisms
What is the cell theory?
- Cells are the simplest, smallest units of life
- Cells may only arise from pre-existing cells
- All metabolic events occur within cells
What happens when you increase cell volume?
It causes issues to the cell membrane
What affects the rate of diffusion?
- Surface area
- Temperature
- Concentration gradient
- Distance
What is the role of the cell membrane?
Acts as protection
What is the role of the golgi apparatus?
It is the receiving and sending center
It receives proteins and delivers to their destinations
What are the roles of a vesicle?
It ships proteins eternally to the nucleus
Secretes proteins to the outside of the cell
What is the lysosome?
It is the stomach cells
What is sent to the lysosome?
Debris, worn out, or damaged parts
What is the mitochondria?
It is the powerhouse of the cell
What is the role of the mitochondria?
Cellular respiration
What do the centrioles aid?
Cell division
What are the roles of the cytoskeleton?
Maintains cell shape
Anchors cell with extracellular matrix
What is the apical part of the cell?
It is the top domain
What is the apical domain of the cell responsible for?
- Protection
- Absorption
- Secretion
What is the basolateral?
It is the side and bottom domain of the cell
What is the basolateral responsible for?
Anchorage and communication to neighboring cells
Define cytoplasm
It is the material between plasma membrane and the nucleus
Define plasma membrane
It encloses most the organelle
What is the role of the plasma membrane?
It organizes and protects the cell
Which head is soluble in water?
Polar/hydrophilic head
Which head is not soluble in water?
Fatty acids/nonpolar head
Define semipermeable
Some substance can flow through it freely
What is the role of cholesterol?
It is used to maintain the stability of the cell
Define cytosol
A viscous, semitransparent fluid substance of cytoplasm in which other elements are suspended
Define cytoplasmic organelles
Specialized cellular compartments or structures, each performing its own job to maintain the life of the cell
Define inclusions
Chemical substances such as glycogen granules and pigment
What is the role of hydrostatic properties?
They help cells maintain their shape
What functions are biological membranes involved in?
- Import and export
- Compartmentalization
- Cell signaling, they respond to environment
- Cell and nuclear division
- Production of energy intermediates
What are the characteristics of polar heads?
- Made by glycerol and phosphate
- The tail is made of 2 fatty acids, hydrophobic cells
- Increases the flexibility of the cell membrane
What is the percentage breakdown for lipids?
75% phospholipids
5% glycolipids
20% cholesterol
Define phosphate heads
They are polar and hydrophilic
Define fatty acid tails
They are non polar hydrophobic
Define glycolipids
Lipids with polar sugar groups on outer membrane surface
What is the role of cholesterol?
It increases membrane stability
What are the two types of membrane proteins?
- Integral proteins
2. Peripheral proteins
What are the characteristics of integral proteins?
- They are firmly inserted into the membrane
- They have hydrophobic and hydrophilic regions
What is the function of integral proteins?
They transport proteins, enzymes, or receptors
What are the characteristics of peripheral proteins?
- They are loosely attached to integral proteins
- They include filaments on intracellular/extracellular surface for membrane support
What is the function of peripheral proteins?
They are enzymes or motor proteins that are involved in mechanical functions, such as changing cell shape during cell division and muscle cell contraction
What are the 6 functions of membrane proteins?
- Transporter
- Cell-surface receptor
- Attachment to cytoskeleton and extracellular matrix
- Enzyme
- Intercellular joining
- Cell-to-cell adhesion
Define osmosis
Movement of water across a membrane
What kind of energy is osmosis an example of?
Kinetic energy
Define tonicity
How a solution affects cell volume
Define simple diffusion
Substances diffuse directly though the lipid bilayer
What substances diffuse during simple diffusion?
Gases, steroid hormones, and fatty acids
Define facilitated diffusion
The transported substance either binds to carrier proteins in the membrane and is ferried across or moves through water-filled channel proteins
Define carriers
Transmembrane proteins that are specific for transporting certain polar molecules or classes of molecules, ones that are too large to pass through membrane channels
Define vesicular transport
The transport of large particles and macromolecules across plasma membranes
Define exocytosis
Secretes substance into the extracellular space
Define endocytosis
Eats the large molecules into the cells
Define phagocytosis
Pseudopods engulf solids and bring them into the cell’s interior
Define filtration
It is a form of hydrostatic pressure, it is the formation of kidney filtrate
What is the role of cell junctions?
To aid or inhibit movement of molecules between or past cells and also see to tie cells together into tightly knit communities
What are 3 types of cell junctions
- Tight junctions
- Desmosomes
- Gap junctions
What are tight junctions?
A series of integral protein molecules in the plasma membranes of adjacent cells fuse together like the zipper of a Ziploc bag
What is the role of tight junctions?
They help prevent molecules from passing through the extracellular space between adjacent cells and restrict the movements of membrane proteins
Define desmosomes
They serve as anchoring junctions, they are mechanical couplings scattered like rivets along the sides of adjacent cells to prevent their separation
What is the role of desmosomes?
They bind neighboring cells together into sheets and also contribute to a continuous internal network of strong fibers
Define gap junctions
It is communication junction that determines what kind of stuff passes through them
Where are gap junctions found?
The heart and smooth muscle
What are the 5 types of membranous cytoplasmic organelles?
- Mitochondria
- Peroxisomes
- Lysosomes
- Endoplasmic reticulum
- Golgi apparatus
What are the 3 types of non membranous cytoplasmic organelles?
- Cytoskeleton
- Centrioles
- Ribosomes
Define mitochondria
- It is a double membrane structure with shelf-like cristae
- Provides most of the cell’s ATP via aerobic cellular respiration
- Contains their own DNA and RNA
- Releases carbon dioxide as waste
Define ribosomes
- Granules containing protein and rRNA
- Site of protein synthesis
- Synthesize soluble proteins that function in cytosol or other organelles
- Membrane-bound ribosomes synthesize proteins to be incorporated into membrane, lysosomes, or exported from cells
Define endoplasmic reticulum
- They are interconnected tubes and membranes enclosing cisternae
- It is continuous with nuclear membrane
- There are two varieties rough and smooth ER
Define smooth ER
They are tubules arranged in looping networks
What are the roles of smooth ER
It synthesizes phospholipids for cell membranes, and catalyzes reactions in carious organs of the body
Where is smooth ER found?
liver
testes
intestinal cells
skeletal and cardiac muscle
Define Golgi apparatus
It is stacked, flattened membranous sacs, proteins pass through to trans face, secretory vesicles leave the trans face
What is the function of Golgi apparatus?
It modifies, concentrates, and packages proteins
Transports vessels from ER fuse to cis face
Define peroxisomes
Membranous sacs containing oxidases and catalase
What is role of peroxisomes?
Detoxify harmful or toxic substances, and neutralize dangerous free radicals
Define lysosomes
They are spherical membranous bags containing digestive enzymes
What are the roles of lysosomes?
- Digest ingested bacteria, viruses, and toxins
- Degrade nonfunctional organelles
- Breakdown non useful tissue
- Breakdown bone to release Ca2+
Where are secretory lysosomes found?
White blood cells
Immune cells
Melanocytes
What is the endosymbiont theory?
The mitochondria used to be a single cell that ended up getting into the host cell chloroplasts survived and works together
What are the characteristics of the nucleus?
- Contains nuclear envelope, nucleoli, chromatin, and distinct compartments that are rich in proteins
- Gene-containing control center of the cell
- Contains the genetic library for most cellular proteins
- Controls proteins synthesis
Define nuclear envelope
- Selectively permeable double membrane barrier containing pores
- Encloses jellylike nucleoplasm
- Outer membrane is continuous with the rough ER is studded with ribosomes
- Inner membrane in line with the nuclear lamina
- Pore complex regulates transport of large molecules into and out of the nucleus
Define nucleolus
Dark-staining spheric bodies within the nucleus
Site of ribosome production
Define cytoskeleton
The skeleton of the cell
Consists of microtubules, microfilaments, and intermediate filaments
Define centrioles
Small barrel-shaped organelles located in the centrosome near the nucleus
Pinwheel array of non triplets of microtubules
What is the role of centrioles
- Organize mitotic spindle during mitosis
- Form the bases of cilia and flagella
Define cilia
It is a whiplike, motile cellular extension on exposed surfaces of certain cells
Moves substances in one direction across cell surfaces
Define osteocyte
Bone cells
Define osteoblast
Cells that form the bones
Define osteoclast
Chews off the damaged bone tissue
Define osteoprogenitor
It is the maturing center of the born cell
Define osteoid
It is bone matrix that is made by collagen
Define periosteum
It contains osteoblasts that surrounds the bone
Explain endochondral ossification
- Hyaline cartilage starts out
- Cartilage start to calcify
- A cavity of spongy bone and blood vessels start to form
- Two more officiation centers attach to the top and bottoms of the bone
- Cartilage surrounds the bone, there is now cartilage in between the plates of the bone
Define diaphysis
Elongated shaft of a long bone
Define epiphysis
End of a long bone
Define medullary cavity
The central cavity of a long bone. Contains yellow or red marrow
Define articular cartilage
Hyaline cartilage covering bone ends at moveable joints
Define periosteum
Double-layered connective tissue that covers and nourishes the bone
Define blood vessels
Brings blood to the heart
Define spongy bone
Internal layer of skeletal bone
Where is cartilage found in your body now?
Bridge of nose
Parts of ribs
Joints
What is the role of epiphyseal plates?
They allow for growth during childhood
Define ostoeporosis
It is the result of declining bone mass
The osteoclasts outperform osteoblasts
What are the risk factors of osteoporosis
Increased age and lower estrogen in women
Where are maxillary sinuses found?
Both sides of our cheeks
Where is the front sinus found?
Above our eyes
Where is our ethmoid sinus found
Around the nose
Where is the cribriform plate found
In the frontal bone
What is the purpose of the cribriform plate?
Has holes in it for the olfactory nerves to pass through
Where is the sella turcica?
The center of the skull
What is the role of the sella turcica?
Protects the hypothalamus and pituitary gland
What is the role of the foramen magnum?
It is where the spinal cord enters the skull
Where is the maxilla
It is the top of the mouth
What are occipital condyles?
They are define bony elements that smooth
Where is the hyoid apparatus?
It is in the throat
What is the role of the hyoid?
It separates the larynx from the skull. It determines the range of sounds that we can speak
What are the fontanelles made up of?
Fibrous membrane
What is the role of the fontanelles?
Allows the skull to be compressed during birth
Allows the brain to grow
What are the three sections of the vertebra
- Cervical
- Thoracic
- Lumbar
How many vertebra in the cervical area?
7
How many vertebra are in the thoracic area?
12
How many vertebra are in the lumbar area?
5
What is C1 called
Atlas
What is C2 called?
Axis
What is the pectoral shoulder girdle made up of?
- The clavicle
2. The scapula
What is the role of the clavicle
It is a brace over the movement of the arm
What is the role of the scapula?
To help with muscle attachment
What bones make up the pelvis?
- ilium
- Ischium
- Pubic bone
What is the role of the pelvis ?
Protects reproductive organs, urinary bladder, and part of the large intestine
Define kinetic energy
Energy of motion
Composed of mass and speed
How do you increase kinetic energy?
By increasing temperature
Define potential energy
It is stored energy
It can be transformed into kinetic energy
What is the first law of thermodynamics?
Energy cannot be created or destroyed
Energy can only change from one form to another
What is the second law of thermodynamics
Thermodynamics are continuously increasing
What is the free energy formula?
G= H - TS G= energy available to do work H= energy in a molecule's chemical bonds T= absolute temperature S= unavailable energy
Define endergonic reaction
It is more energy at the end of the reaction than there was at the beginning
Has to be supplied the energy
Define exergonic reaction
It releases free energy
It is spontaneous
What are the four elements that make up 96% of our body?
- Carbon
- Oxygen
- Hydrogen
- Nitrogen
What is the valence shell and what is it made up of?
It is the outside of the nucleus
It is made up of electrons
What is the nucleus made up of?
Protons and neutrons
What are isotopes?
A variation of an element
Has the same number of protons but different amount of neurons
How many electrons can be in the first shell?
2 electrons
How many electrons can be in the second shell?
10 electrons
How many electrons can be in the third shell?
18 electrons
What is an ionic bond?
It is when the electrons are completely transferred from one atom to another
What are ions
Charged particles
What are anions?
Negatively-charged ions
What are cations?
Positively charged ions
What are covalent bonds?
Sharing electrons
What are hydrogen bonds?
Provides attraction between molecules, hydrogen is attracted to negative portion of polar molecules
define synthesis
It is when atoms or molecules combine
Define decomposition
A molecule is broken down
Energy is released
Define inorganic compounds
Compounds that do not contain carbon
What is the pH of acids?
They have a low pH
An acidic/sour taste
What are examples of bases?
Baking soda Sea water Bleach Blood Semen
What are the pH levels for bases?
Above 7
What are examples of monosaccharide?
- Glucose
- Galactose
- Fructose
- Deoxyribose
- Ribose
What are examples of disaccharides?
- Sucrose = glucose and fructose
- Maltose= glucose and glucose
- Lactose= glucose and galactose
How many different amino acids are there?
20 protein amino acids
What is the role of protein?
Construction material for body tissues
Cell function
Acts as an enzyme, hormone, and antibody
What denatures a protein?
Heat
When pH levels change
When they lose the third level of amino acid chains
Define enzymes
Biological catalysts
What is the role of biological catalysts?
Speeds up the chemical reaction