lecture exam 1 Flashcards
three chemcical bonds
hydrogen, covalent, and ionic bonds
order of the least strongest to strongest bond
hydrogen, ionic, polar covalent, non-polar covalent
polar cavelnt molecule
water
four types of inorganic compounds
water, acids, bases, salts (ionic-anions and cations in water), do not contain carbon atoms in chain
universal solvent
water because it is abundant, high heat capacity, and a thermoregulator
buffers
acid-balance regulators, able to resis abrupt changes to the pH by binding to H+ when pH drops
organic compounds
carbs (-saccharides), lipids (fats), nucleic acids (DNA and RNA), proteins
disaccharides
sucrose, lacose, maltose (linked by glycosidic bonds)
primary protien structure
linear chain
secondary protein structure
alphs helox or beta pleated sheet
tertiary protein structure
proteins coil to make 3D shape
quaternary protein structure
two or more polypeptide chains held by disulfide bonds
structural proteins
secondary structure, insoluble, mechanical support and are in an strand-like shape
fucntional proteins
soluble, (3/4 structure), ball-like, sensitive to low pH and high temp
fibrous proteins
structural proteins
denaturation
high temp and low pH levels
lipids
neutral fats, phospholpids, steriods, eicosanoids
unsaturated fats
double covalent bonds, liquid and plant based
saturated fats
single covalent bond, solid and animal based
what causes LDL proteins
the excess consumption of saturated fats
good cholesterol
HDLs
bad cholesterol
LDLs, the excess cholesterol increases and the amount of plaque increases causing it to clog the arteries and prevent blood flow
phospholipids
glycerol bakcbone,2 fatty acid chain, and a phosphorous containing group
what receptors fo steriodogenic cells express?
LDL receptors because LDL binds to LDL receptors o the surface of steriodogenic cells and are taken in via receptor-mediated endocytosis
eicosanoids
cyclooxygenase produces prostaglandin
use of aspirin
asprin manages thromboembolic disorders because it inhibits cyclooxygenase. thromboxane mediated blood clot formation and aspirin combats these disorders which is why it’s used to prevent thrombi and emboli from forming
three major parts of a cell
plasma membrane, cytoplasm, and nucleus
plasma membrane
boundary of cell
cytoplasm
interior of cell b/w membrane and nucleus
nucleus
contains genes which control activities in the cell
function of cholesterol in membrane
embedded in the tails of phospholipids (fatty acid tails), this stabilizes the unsaturated fats which stabilizes the membrane
integral proteins
important for movement of cells across the membrane
peripheral proteins
attached to the surface of integral proteins
transmembrane proteins
allows the transportation of specific substances along the membrane
membrane junctions
tight jucntions, desmosomes, gap junctions
tight junctions
impermeable junctions
desmosomes
anchoring junctions
gap junctions
communicating junctions
connexons
allow transfer of ions and small signaling molecules
linker proteins
are short amino acid sequences that separate mulitple domain in a single protein
membrane transport
active and passive processes
passive processes
simple diffusion, facilitated diffusion, osmosis, and filtration
simple diffusion
small, nonpolar molecules pass through lipid bilayer of the membrane (hydrophobic)
facilitated diffusion
facilitated polar, hydrophobic substances that cannot cross the bilayer without carrier proteins (transports integral proteins)
osmosis
movement of water from low to high concentrations through a semipermeable membrane (aquaporins)
filtration
down pressure gradient (no ATP) (urine formation through kidneys)
tonicity
0.5 and 9 NaCl = isotonic
less than that = hypotonic (bursts)
more tha that = hypertonic (shrink)
active processes
active transport and vesicular transport (bulk transport)
active transport
movement from low to high concentration gradients (solute pumping) (Na/K pump) against gradient
vesicular transport
endocytosis and exocytosis
endocytosis
movement into cells (nutrients etc)
exocytosis
movement out of cells (protein secretion)
three types of endocytosis
phagocytosis, pinocytosis, receptor-mediated endocytosis
phagocytosis
moves solid particles from exterior into the cells
pinocytosis
movement of solutio into cels by enclosing the soution into escile (pinocytic vesicles)
receptor-mediated endocytosis
substance binds to specific receptors on the surface of the cell and are taken into the cell
mitochondria
powers plants
ribosomes
site of protein synthesis