Lecture 9: Somatosensory Pathways Part 1 Flashcards

1
Q

What information does the PCML and trigeminothalamic pathway transmit?

A

Discriminative Touch
Pressure
Vibration
Proprioception

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2
Q

What is two point discrimination?

A

Ability to discriminate between two stimuli simultaneously

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3
Q

What areas would have high density of tactile receptors?

A

Digits

Perioral region

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4
Q

What areas would have low density of tactile receptors?

A

Back

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5
Q

Small receptive fields have ____ receptor density.

Large receptive fields have ____ receptor density.

A

Small receptive fields have HIGH receptor density.

Large receptive fields have LOW receptor density.

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6
Q

What type of axons are primary afferent fibers?

A

Sensory

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7
Q

Where do primary afferent fibers have their cell bodies?

A

Dorsal Root Ganglion

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8
Q

In the PCML pathway, where do primary afferent fibers enter the spinal cord?

A

Medial division of posterior root

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9
Q

In the PCML pathway, where do primary afferent fibers travel after entering the spinal cord via the posterior root?

A

Posterior Columns: Fasciculus Gracilis and Cuneatus

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10
Q

Where is Fasciculus Gracilis found (both generally in the SC and in an SC cross section)?

A

Found in whole spinal cord but receives input from sacral Region to T6 (located medially)

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11
Q

Where is Fasciculus Cuneatus found (both generally in the SC and in an SC cross section)?

A

T6 and above (located laterally)

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12
Q

Which fibers are found more medially?

A

Sacral and the more rostral you go, the more lateral those fibers are found

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13
Q

What supplies the posterior columns?

A

Posterior Spinal Artery

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14
Q

If the PCML pathway is affected from a spinal cord lesion, what can happen?

A

Ipsilateral reduction or loss of discriminative, positional, and vibratory tactile sensations
Will happen at and below level of injury

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15
Q

What is sensory ataxia?

A

Loss of muscle tendon reflex and proprioceptive losses from extremities due to lack of sensory input
Can lead to difficulty walking and wide based stance

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16
Q

In the PCML pathway, where are 2nd order neurons found?

A

Gracile and Cuneate Nuclei in the posterior medulla

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17
Q

Where are the gracile and cuneate nuclei receiving their input from?

A

First order neurons (primary afferents) from ipsilateral dorsal root ganglion

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18
Q

What are internal arcuate fibers?

A

After synapsing at the gracile and cuneate nuclei, they are the fibers that cross anteromedially in the medulla

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19
Q

What is medial lemniscus?

A

The new name of the fibers after they cross at the medulla until they terminate

20
Q

In the medial lemniscus, where do the upper and lower extremity fibers now reside after the rotation in the pons?

A

Upper: Medial
Lower: Lateral

21
Q

Where does the medial lemniscus terminate?

A

Ventral Posterolateral Nucleus of the Thalamus

22
Q

What supplies the medial lemniscus?

A

Anterior Spinal Artery

23
Q

What supplies the Ventral Posterolateral Nucleus of the Thalamus?

A

Thalamogeniculate Branches of Posterior Cerebral Artery

24
Q

From the Ventral Posterolateral Nucleus of the Thalamus, where do the third order neurons go to?

A

Primary and Secondary Somatosensory Cortices

25
How do third third order neurons reach the somatosensory cortices?
Via Posterior Limb of Internal Capsule
26
What compromises the Primary Somatosensory Cortex (S1)?
Postcentral gyrus and Posterior Paracentral Gyrus
27
What are the Brodmann Areas of the Primary Somatosensory Cortex?
31, 3b, 1, and 2
28
If there is a lesion to the Middle Cerebral Artery, where would there be tactile loss?
Contralateral upper body and face
29
If there is a lesion to the Anterior Cerebral Artery, where would there be tactile loss?
Contralateral lower limb
30
What does the secondary somatosensory cortex sense?
Inner face
31
Where does secondary somatosensory cortex gets its input from?
Ipsilateral SI cortex and Ventral Posterior Inferior Nucleus of the Thalamus
32
What happens if the parietal cortical region is lesioned?
Agnosia: cannot recognize own limb
33
What is the role the mesencephalic nucleus?
Conveys unconscious proprioceptive afferents and pressure afferents from TMJ, masticatory, and extraocular muscles
34
What is the role the principal/chief sensory nucleus?
Discriminative touch and pressure from face
35
What is the role the spinal nucleus?
Pain, temperature, and non-discriminative touch from face
36
In the Sensory Trigeminothalamic Pathway, where are primary afferents from?
Trigeminal Ganglion
37
In the Sensory Trigeminothalamic Pathway, where are 2nd order neurons found?
Principal/Chief Sensory Nucleus
38
What supplies the Principal/Chief Sensory Nucleus?
Superior Cerebellar Artery | Long Circumferential branches of Basilar Artery
39
What are the two divisions of the principal/chief sensory nucleus and what do they receive information from?
Dorsomedial: Oral Cavity Ventrolateral: V1, V2, V3
40
How does the dorsomedial division reach the thalamus?
Travels ipsilaterally via posterior trigeminothalamic tract to
41
How does the ventrolateral division reach the thalamus?
Travels contralaterally via anterior trigeminothalamic tract
42
Where do both anterior and posterior trigeminothalamic tracts synapse at?
Ventral Posteromedial Nucleus of the Thalamus - Oral Cavity: Medial part of nucleus - External Face: Lateral part of nucleus
43
From the Ventral Posteromedial Nucleus of the Thalamus, where do the third order neurons go to?
Primary somatosensory nucleus via posterior limb of internal capsule
44
What reflex is initiated when there is a downward tap on the chin?
Jaw-Jaw Reflex: Stretching of masseter muscle causes it to contract bilaterally
45
What is the pathway of a jaw-jaw reflex?
1. Innervation of Mesencephalic Trigeminal Neuron 2. Innervation of masseter muscle spindle 3. Synapse on trigeminal motor neuron