Lecture 9: adaptive immunity

Question 1

main features:

Answer 1

• Specificity
• Memory
• Tolerance

Question 2

T & B Lymphocytes:

Answer 2

T- and B-cells are highly specialised defender cells - different groups of cells are tailored to different germs. When your body is infected with a particular germ, only the T- and B-cells that recognise it will respond

Question 3

where do T & B Lymphocytes come from?

Answer 3

bone marrow (red)

Question 4

t lymphocytes:

Answer 4

cell-mediated immunity

Question 5

B cells:

Answer 5

antibody-mediated immunity

Question 6

major players in adaptive immunity :

Answer 6

• Lymphoid tissue e.g. lymph nodes
• Antigen – presenting cells (APC’s – terminology imprecise)
• Follicular dendritic cells
• T – lymphocytes
• B – lymphocytes

Question 7

APC’s

Answer 7

-Display fragments of invading pathogens on their surface
Present them to (other) immune system cells – especially T lymphocytes
-Fixed and free macrophages e.g. Kupffer cells, monocytes, microglia
-Epithelia and endothelia
- B lymphocytes