Lecture 9 Flashcards
1
Q
What does intracellular calcium interact with the cause contracion?
A
Myofilaments/sarcomere
2
Q
What is the H zone of a sarcomere?
A
Just thick filaments
3
Q
What are the thin filaments attached to?
A
The Z lines
4
Q
What are two structural specialisations of cardiomyocytes that allow coordinated contraction?
A
T tubules convolute at every sarcomere. SR is positioned closely to the T tubule
5
Q
Why do elementary calcium events occur?
A
RyR realises SR calcium store is too full
6
Q
What percentage of cytosolic calcium comes from the L type VOC?
A
5-155
7
Q
What removes cytosolic calcium?
A
Na/Ca exchanger and SERCA.
