Lecture 9 & 10 Genetics

Question 1

heritable changes to genomes

Answer 1

1. mutation
2. conjugation
   - gene from chromosome becomes f- factor
3. transformation
   uptake of naked dna from environment
4. transduction
   virus mediated transfer of bacteria
5. genetic engineering

Question 2

Inducing mutation

Answer 2

base analog
intercalating
dna modifying
physical

Question 3

Detectable mutations

Answer 3

missense, nonsense, frameshift

Question 4

cause of dna

Answer 4

-tautomerization; base change
-insetion/delettion; replicaion error
lesion of dna
-depurination

Question 5

mRNA arrangement

Answer 5

polycistronic
no poly A tail
no 5’ cap