Lecture 8: RNA Structure, Folds and Function Flashcards by Deleted Deleted | Brainscape

Q

What is pre-mRNA spliced by ?

A

Major ir minor spliceosomes

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Q

What does the major spliceosome contain ?

A

U1, U2, U4, U5 and U6 snRNP

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Q

Where do U1 and U2 snRNP assemble ?

A

Intron

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Q

What joins the assemnly at the intron ?

A

U4/6 which is then joined by U5 tri-snRNP

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Q

What is transfer RNA processed by ?

A

RNA ribozyme-RNase P

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Q

What are microRNA in eukaryotes ?

A

Regulators

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Q

What do microRNA do ?

A

Bind to mRNA

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Q

What does a perfect match result in ?

A

mRNA degradation

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Q

What is a germline type miRNA?

A

Piwi interacting RNA

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Q

What inhibits gene expression in cis ?

A

Xist long non-coding RNA

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Q

What inhibits gene expression in trans ?

A

HOTAIR (Hox transcript antisense intergenic RNA)

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