Lecture 8 Flashcards
0
Q
Type 2 sensitivity and response
A
surface antigen
IgG response
1
Q
Type 1 Hypersensitivity reaction and response
A
Allergy
IgE response –> Th2
2
Q
Type 3 hypersensitivity and response
A
soluble antigen
IgG response
3
Q
Type 4 hypersensitivity and response
A
T cell mediated (delayed type hypersensitivity)
4
Q
Describe a Type 2 hypersensitivity reaction with someone with a penicillin allergy
A
penicillin binds to surface antigen on the RBC
Penicillin seen as foreign, therefore you mount a response
YOU make IgG to penicillin (opsonize)
Macrophage comes and clears opsonized RBC
HEMOLYTIC ANEMIA