Lecture 8 Flashcards

0
Q

Type 2 sensitivity and response

A

surface antigen

IgG response

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1
Q

Type 1 Hypersensitivity reaction and response

A

Allergy

IgE response –> Th2

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2
Q

Type 3 hypersensitivity and response

A

soluble antigen

IgG response

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3
Q

Type 4 hypersensitivity and response

A

T cell mediated (delayed type hypersensitivity)

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4
Q

Describe a Type 2 hypersensitivity reaction with someone with a penicillin allergy

A

penicillin binds to surface antigen on the RBC
Penicillin seen as foreign, therefore you mount a response
YOU make IgG to penicillin (opsonize)
Macrophage comes and clears opsonized RBC
HEMOLYTIC ANEMIA

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