Lecture 8 Flashcards
1
Q
Strategies in adressing uncertainty in PBK estimation?
A
- Determine PBK modeling
- Probabilistic population PBK modelling
- Probabilistic population PBK + CMED modelling
2
Q
Exposure-led approach to determine…
A
protection through a bioactivity exposure ratio (BER)
3
Q
focus on weight of evidence to show…
A
tools can be integrated to make a safety decision
4
Q
How to accept NAMs?
A
ensure quality of tools and include estimations of uncertainty to aid acceptance