Lecture 8 Flashcards

1
Q

Strategies in adressing uncertainty in PBK estimation?

A
  1. Determine PBK modeling
  2. Probabilistic population PBK modelling
  3. Probabilistic population PBK + CMED modelling
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2
Q

Exposure-led approach to determine…

A

protection through a bioactivity exposure ratio (BER)

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3
Q

focus on weight of evidence to show…

A

tools can be integrated to make a safety decision

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4
Q

How to accept NAMs?

A

ensure quality of tools and include estimations of uncertainty to aid acceptance

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