LECTURE 7 - memory and learning Flashcards
What is the difference between implicit and explicit memory?
Explicit (declarative) = facts or events, easy to learn easy to forget, available for conscious recollection
Implicit (non-declarative) = things you learn to do, less likely to be forgotten, requires repetition, not available for conscious recollection
How is declarative memory split?
Long term memory: recalled after a long time
Short term memory: last for a short time, vulnerable to disruption
What are the two theories of memory consolidation?
- Sensory information –> short term –> long term
consolidation occurs together - Sensory info –> short term +
sensory info –> long term
occurs separately
Some believe first you have STM then it is consolidated, others believe consolidation are parallel processes occurring independently
What is amnesia?
- loss of memory and learning ability
- can be caused by concussion, tumour, stroke, alcoholism, encephalitis
What is the difference between the different types of amnesia?
Retrograde = forget things before event
Anterograde = cannot form new memories
Transient global amnesia = lose memory of everything for a short period of time
What experiment did Lashley perform and what were the results?
- surgically induced brain lesions by damaging or removing cortex of rat’s brain either before or after maze training
- He concluded the severity of the deficit was related to the size but not the location of the lesion
- He concluded all cortical areas involved equally in memory storage
HOWEVER - He damaged interconnecting areas in brain because the brain is so small so he was not right
What role does the cortex have in declarative memory?
- Information from sensory modality stored in cortical region that serves that modality
- Visual memory: extrastriatal cortex
- Temporal lobes : complex memories
What role does the medial temporal lobe have in memory processing?
- consolidation of declarative memory
- temporary memory storage in the MTL - consolidation in cortex
Hippocampus
- spatial memory - place cells
- working memory - related to ongoing behaviour
- relational memory - ties together things happening at the time of memory storage
What are the consequences of a temporal lobectomy?
- loss of STM (declarative)
- loss of anterograde and retrograde memory
- maintained procedural memory
- maintained some LTM (childhood)
Why have one?
some forms of epilepsy can only be treated by removing the temporal lobe
What is Hebb’s theory?
(1949 - Organisation of behaviour)
- claims that an increase in synaptic efficacy arises from a presynaptic cell’s repeated and persistent stimulation of a postsynaptic cell
- attempts to explain synaptic plasticity, the adaptation of brain neurones during the learning process
When an axon of cell A is near enough to excite a cell B and repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells such that A’s efficiency, as one of the cells firing B, is increased
What is the engram of an object?
- assembly of cortical cells activated by the external stimulus
(engram = memory trace)
Describe cell assembly in the brain
Reciprocally interconnected: STM
Fire together wire together: LT consolidation
What is the new model of learning that comes from Hebb’s theory?
- modifications of synaptic transmission
- synaptic transmission triggered by neuronal activity
- alterations of existing synapses
How can synapses become stronger?
‘Neurones that fire together, wire together’
When strong activation of synapses leads to firing of the postsynaptic neurone (in time with the presynaptic neurone), this leads to potentiation of the postsynaptic response
What is LTP?
Long term potentiation = persistent increase in synaptic strength following high-frequency stimulation of a chemical synapse
