Lecture 7: Contraception Flashcards
How common are unintended pregnancies?
45%
What is the main cause of 40% of unwanted pregnancies?
Not using birth control
Top 3 reasons for not using contraception
- They dont care if they get pregnant
- Worried about the side effects
- Did not think they’d get pregnant
What is the general consensus regarding contraceptives in adolescents?
Give it to them!
What other disorders may use contraceptives as a form of tx? (3)
- Endometriosis
- PCOS
- Premenstrual dysphoric disorder (PMDD)
What are the 4 most effective contraceptive methods?
- Implant (F)
- Vasectomy (M)
- Tubal occlusion (F)
- IUD (F)
What methods are considered the worse for contraception?
- Coitus interruptus (pull-out method)
- Postcoital douche
- Periodic abstinence
- Lactational amenorrhea
Not using any birth control products
When is it appropriate to restart contraceptives after delivery?
3 months after
What is the most effective determinant of periodic abstinence?
Serum LH peak
What is the MC method of periodic abstinence?
Calendar method
It is also the least reliable
What is the billings method/cervical mucus method for periodic abstinence?
- Checking ovulation by checking cervical mucus
- Thin/watery = right before ovulation
- Thicker = rest of cycle
Thin/watery = you are about to ovulate
What is the likely most effective method for periodic abstinence?
Symptothermal: Cervical mucus + temperature
thick mucus + 3rd day after elevated temp should be safe?
How does temperature vary in ovulation?
- Drops slightly 24-36 hrs before ovulation
- 3rd day after onset of elevated temp = fertile period over
What is in COC (combination oral contraceptives)?
- Estrogen: ethanyl estradiol (MC), mestranol, 17b-estradiol, or estradiol valerate
- Progestin: norethindrone, levonorgestrel, desogestrel, norgestimate, drosperinone
Which progestin ingredient is a spironolactone analogue?
Drosperinone, which is less androgenic but higher VTE risk.
What is the cycle of COCs?
- 21 days of active hormones
- 7 days of placebo
Newer is 24-4
What should patients expect after stopping active COCs?
Withdrawal bleed 2-5 days after
What are the 3 ways of beginning the administration of COCs?
- Ideal: first day of menstrual cycle
- Traditional: first sunday following menses
- Quickstart: day you get it
When is missing a pill concerning/emergency?
Any missed pill + coitus in past 5 days
What is the MOA of COCs?
Suppression of ovulation
Alters consistency of mucus
Makes endometrium less receptive to implantation
What is the MC drug class that interacts with COCs?
Anticonvulsants
What are the benefits of using COCs? (8)
- Reduced ovarian cx
- Reduced endometrial cx
- Improved bone mass
- Decreased progression of RA
- Improves acne
- Lower risk of ectopic + PID
- Decreased risk of benign fibrocystic breast dz
- Improvement in dysmenorrhea and premenstrual s/s
What are the major SEs of COCs? (6)
- VTE
- MI
- Stroke
- Liver dz
- Cervical dysplasia/cancer
- Breast cancer (controversial)
clotsx3, liver + cervix
CIs to COCs (8)
- Pregnant
- Undxd vaginal bleeding
- Migraine w/ aura
- Prior hx of VTE/MI/Stroke
- Increased risk for CV issues (SLE, DM, HTN uncontrolled)
- Smoking over 35
- Current/hx of breast cx
- Active liver dz
Bottom 5 are all things it enhances
What should we keep in mind regarding POCs (progestin-only contraceptives)?
Does not suppress ovulation
Estrogen suppresses ovulation by inhibiting FSH
Why would someone take POCs?
- No estrogen effects
- No special sequence for pill-taking
Cons of using POCs? (3)
- Must take at same time daily
- Higher rates of irregular bleeding
- Higher overall pregnancy rate
CIs to POCs (5)?
- Unexplained uterine bleeding
- Breast cx
- Hepatic neoplasms
- Pregnancy
- Active liver dz
Primarily liver issues
What are the 3 methods for emergency contraception?
- Yuzpe method
- Levonorgestrel
- Copper IUD
After you have unprotected sex or misused contraceptive
Describe the Yuzpe method, including dosages and dosing
- COCs containing levonorgestrel
- 100mcg ethinyl estradiol + 500-600mcg levono
- 2 doses, 12 hrs apart
- 1st dose must be taken within 72 hrs of sex