Lecture 7 - Assessment of a treatment

Question 1

when asking a focused question, we focus on PICO:
P=
I=
C=
O=

Answer 1

population;
intervention;
comparison;
outcome

Question 2

most important way to reduce bias?

Answer 2

randomization

Question 3

in order to minimize bias from patients dropping out of a study, they should be analyzed as _____ results in the group they were originally assigned

Answer 3

negative

Question 4

treatment response calculations using Event rate for treatment vs control:

relative risk =
relative risk reduction =
absolute risk reduction =

Answer 4

RR = event with treatment / event with control;

RRR = 1 - RR;

ARR = event with control - event with treatment

Question 5

in regards to response to treatment, you want RR to be ___ than 1, RRR to be a ____ number

Answer 5

less;

positive

Question 6

equation for number needed to treat?

Answer 6

1 / ARR

Question 7

should a claim for decreased risk be reported as ARR or RRR?

Answer 7

ARR

Question 8

for a treatment result to be meaningful, the confidence interval of RR should not include ____ and the RRR should not include ___

Answer 8

1, 0