Lecture #7

Question 1

What is a human pedigree?

Answer 1

shows the relationship between members of a family

Question 2

What does a double line mean in a human pedigree?

Answer 2

mating between relatives

Question 3

What are characteristics of autosomal dominant traits?

Answer 3

appears equally in males and females
unaffected people do not transmit the trait
affected people have at least one affected parent
for matings with one affected parent, 1/2 the offspring are affected
affected individuals appear in every generation

Question 4

How do mammals adapt to unequal dosage of x-linked genes in males and females?

Answer 4

by inactivating one of the two X chromosomes in females

Question 5

How do drosophila adapt to unequal dosage of x-linked genes in males and females?

Answer 5

hyper-activating the single X chromosomes in males

Question 6

How do C. elegans adapt to unequal dosage of x-linked genes in males and females?

Answer 6

each of the two x chromosomes has reduced activity, that are collectively equal to the single X in males

Question 7

What is the barr body?

Answer 7

the in activity highly condensed X chromosome

Question 8

What are the characteristics of autosomal recessive traits?

Answer 8

appears equally in males and females
tends to skip generations
often results from mating between relatives
affected individuals can have unaffected parents