lecture 6 Flashcards
Are introns really “junk” DNA?
No, we don’t really know too much what amount is junk DNA.
The Encyclopedia of DNA elements (ENCODE) Project has now determined that _____ (percent) of the human genome is functional. Of that percentage though, only _____ (percent) is defined as transcriptionally active, but serve no function (i.e. what they transcribe does not affect your body). Fill in the blanks.
80%, 62%
Which statement does not describe ENCODE’s definition of a functional element?
- DNA sequence results in protein production
- That can be transcribed
- Distinct and reproducible biochemical signature
What is the scientific consensus regarding ENCODE’s findings regarding “junk” DNA?
There is no consensus
According to the video Epigenome The Symphony in Your Cells, what is an epigenome?
The epigenome is a set of chemical modifications to DNA and its associated proteins that can turn genes on or off, without changing the underlying DNA sequence
According to the video Epigenome The Symphony in Your Cells, what are epigenomic changes?
Epigenomic changes are alterations to the chemical modifications of DNA and its associated proteins that can affect gene expression.
According to the video Epigenome The Symphony in Your Cells, what happens during methylation?
When a chemical gets added to the DNA and it Prime a gene is turned off another type of change has more to do with the arrangement of DNA
According to the video Epigenome The Symphony in Your Cells, when does methylation seem to occur more within human cells?
Older brains
What is the definition of bioinformatics?
Is the application of computer programming mathematics and modeling to the analysis of large sets of biological data
What can you do with the information from bioinformatics?
Looking at the structure and function of a protein
What equipment is needed to complete bioinformatics?
Mass spectroscopy and protein chips
What can you predict with the information from bioinformatics?
Looking at the structure and function of a protein
What findings were discovered, after completing the human genome project, regarding mammal genome size?
All mammals almost have the same number and size of genes
What was another big genetic surprise discovered after the completion of the human genome project?
There is a large number of unfamiliar protein-encoding genes (transcribable genes) that we don’t know what they are making
Some plants have many more genes than humans and mammals. Why?
Plants have multiple duplications