Lecture 5 Endocarditis Flashcards
Infective endocarditis may involve the ____ lining of the heart, the ____ ___, and/or the ____
inner, chordae tendinae, valves
_____ causes acute endocarditis with large vegetations on previously normal valves
S. Aureus
______ causes subacute endocarditis with small vegetations on damaged valves
S. viridans
coag ____ staph ____ can cause endocarditis on prosthetic valves
negative, epidermidis
Strep _____ is seen in the elderly and is present in colon cancer
bovis
most common culture negative encocarditis:
Coxiella burnetti, bartonella, HACEK (Hemophilus, Actinobacillus, Cardiobacterium, Eikenella, Kingella)
Symptoms: "FROM JANE" F = R = O = M =
fever, Roth spots, osler nodes, murmur
Symtpoms: "FROM JANE" J = A = N = E =
Janeway lesions, anemia, Nail-bed hemorrhages, Emboli
other = symptoms of chronic disease ie fever, weight loss, fatigue, night sweats, petechiae
What are Roth spots?
round white spots on retina surrounded by hemorrhages
Osler nodes:
painful or painless?
location?
due to what?
painful (OUCH for osler) raised nodules;
tips of fingers and toes;
vasculitis
Janeway lesion:
painful or painless?
location?
due to what?
painless nodules;
palms/soles;
microemboli
____ ____ are seen in subacute endocarditis in a time course of hours to days
osler nodes
____ ____ are seen in acute endocarditis in a time course of days to weeks
janeway lesions
Major Criteria:
- Lab evidence: at least ___ blood cultures, unless _____
- _____: use echocardiogram
- _______
2, coxiella burnetti;
- endocardial involvement
- new valvular regurg
Minor criteria:
- Predisposing heart condition risk
- ____
- _____ phenomenon such as emboli, hemorrhages
- _____ phenomenon such as glomerulonephritis or positive rheumatoid factor
- positive blood culture (atypical ? don’t know what his notes mean)
- fever,
- vascular.
- immunologic
