Lecture 5 - Body Fluids Flashcards
Total body water (TBW) percentages of total weight of males and females
Male: 60%
Female:50%
ECF percentage
1/3 of TBW
ICF percentage
2/3 of TBW
Blood plasma volume percentage
1/4 of ECF
Interstitial volume percentage
3/4 of ECF
Na mmol/l value in and out of cell
ECF: 140
ICF: 14
K mmol/l value in and out of cell
ECF: 4
ICF: 120
What electrolytes occur more in cell? outside cell?
ICF: K and proteins
ECF: Na, Cl, Ca
Concentration units compared with charge units
Na+: 135-145mmol/L = 135-145mEq/L
Ca++: 2.1- 2.8 mmol/L = 4.2-5.6mEq/L
Cl-: 108mmol/L = 108mEq/L
Protein: 6.0-8.0 g/dL
Concentration units compared with osmolarity
Ca++:
2.1- 2.8 mmol/L = 4.2-5.6 mEq/L = 2.1-2.8 mOsm/L
Na+:
135-145mmol/L = 135-145 mEq/L =135-145 mOsm/L
NaCl:
5mmol/L= 10 mOsm/L
Normal osmolarity in cells
290 mOsm/L
Above is hyperosmotic
Below is hyposmotic
Tonicity solutions
hypertonic – cell shrinks
isotonic – no volume change
hypotonic – cell swells.
Fluid infusion table
Add isotonic NaCl: Extracellular volume increase
Add hypotonic NaCl: Extracellular volume increase, intracellular volume increase, osmolarity decrease
Add hypertonic Nacl: Extracellular volume increase,
Intracellular volume decrease, osmolarity increase.
What would happen if patient was dehydrated?
Extacellular and intracellular volume decrease, osmolarity increase
Drinking sea water or adding salt without water would
Extracellular volume: increase
Intracellular volume: decrease
Osmolarity: increase