lecture-5,6 Flashcards

1
Q

Define homeostasis ?

A

maintance of stable internal environment for the preservation of the normal functioning of cells
-consistency in body temp
needs of cells in multicellular animal are served through exchanges with the internal

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2
Q

What are cells surrounded by ?

A

surrounded by ECF maintaining the
1. ionic composition of ECF
2. solute conc of ECF (determines water balnce )
3. health of cells(eliminating nitrogeneous waste critical for normal cell function

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3
Q

Chemical composition of the body ?

A

body water accounts for about 60% of total body weight
body water divided into locate dwithin cells and located wtihin cells and located outside cells.

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4
Q

What does body water contain ?

A

contains many dissolved ions/substances in solution -fluid
ECF-(outside)
subdivided into plasma and interstitial fluid
ICF-(inside) hydrates interstitial space /interstitium
(consists if connective tissues=collagen)

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5
Q

How does a species maintain homeostasis of its ECF ?

A

-its environment :salt/fresh water ,terrestial
-its lifestyle

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6
Q

What do animal depend on ?

A

excretory systems to maintain
-volume,conc and the composition of their ECF and to excrete wastes
use filtration,secretion,reabsorption to regulate
1. osmolarity
2. ionic composition of ECF

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7
Q

How do bats use blood as ‘fast food’ ?

A

feed on blood of animals once a day
blood=nutritious protein mainly water
bat takes large volumes of blood adn excrete water first
back at home -to digest its meal-noe excrete nitrogenous waste but with minimal water loss–>excretory system switches rapidly from prod lots of dilute urine-to very little conc unrine

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8
Q

Define osmosis ?

A

water moves from a region of high water conc to 1 of lower water conc

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9
Q

How is homeostatic balance maintained in animals ?

A
  1. Remove excess fluid and retain specific ions or solutes
  2. conserve fluids and excrete excess ions or solutes
  3. excrete waste products of nitrogen metabolism ,output :urine
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10
Q

How does water move about ?

A

passive transport of water acrss membrane requires
1. semi-permeable menbrane permitting water but not solute movment
2. a difference in solute concentration

ALL ANIMALS= NO ACTIVE TRANSPORT

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11
Q

What are water channels ?

A

aqua porins
-possess pores allowing water to pass from one side of membrane to the other,according to osmotic gradient
found in tissues which trnsport large volumes of water per day
tubules of kidney

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12
Q

Osmotic pressure in solution ?

A

solute will displace water lowering the water concentration so water will move to left
the amount of pressure that needs to be applied to just stop this movement is OSMOTIC PRESSURE^^^^

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13
Q

Define molarity of solution ?

A

concentration of a substance expressed in moles per litre of that solution

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14
Q

What is Van’t Hoffs law ?

A

dependant on the total number of dissolved particles present in a solution which is measured in osmoles
1 osmole= 1 mole avogadros

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15
Q

Define Osmolarity ?

A

the measure of solute concentration defined as the no of osmoles per litre of solution

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16
Q

Define Osmolality ?

A

no of osmoles per kg of solution

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17
Q

How does water move in fishies ?

A

move from a hypoosmotic (low) to hyperosmotic (highosmotic pressure :fish plasma) solution to make them isomotic
osmotic eqm is reached

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18
Q

How does the osmolarity of ECF & ICF remain the same ?

A

major contribution ICF osmolarity -K+
Major contributions ECF-Na+,Cl- ions
major diff between plasma & ISF is that proteins levels are low in ISF

19
Q

What are non -permeating solutes ?

A

cannot cross cell membranes ;create a ‘persistent’ osmotic gradient
eg. plasma proteins create COLLOID OSMOTIC PRESSURE (oncotic pressure)
means that plasma has a slightly higher osmolarity than ISF –>prevents huge blood loss of fluid volume

20
Q

What are penetrating solution ?

A

can diffuse through cell membrane ;can alter the osmotic-pressure gradient.
Solvent drag=when water is crossin ga membrane ,a solute may ohysically move it

21
Q

What is a isotonic solution ?

A

is one that has the same osmotic pressure as that of the other cells
solutions that are isotonic are not always isotonic in long run

22
Q

Define isotonic solution ?

A

one into which cells can be placed without their volumes being affected

23
Q

Define Hypotonic solution ?

A

has an osmotic pressure less than that of cells ;cells will swell because of an osmotic influx of water

24
Q

Define Hypertonic solution ?

A

Has greater osmotic pressure than that of cells ;cell will shrink because of osmotic water loss

25
What is tonicity ?
measure of osmolarity or osmolality
26
What is stenohaline ?
species that can tolerate only a narrow range of environmental /ambient salinity most open oceans invertebrates species are stenohaline osmoconformers :rarely experience dilution off seawater
27
Define euryhaline ?
species especially estuarine species can survive wide range of salinity are likely osmosregulators
28
What is the diff between osmoconformers vs osmoregulators ?
aqautic animals either conform to osmolarity or they expend metabolic energy to maintain constant internal osmolarity most marine invertebrates =osmoconformers
29
How does osmolarity in ECF work ?
is in eqm with external environment energy saving other aqautic /marine invertbrates are osmoregulators maintains constant internal osmolarity
30
Eg of a sea thing that osmoconforms /osmoregulates in diff conditons ?
Brine shrimp Hyperosmotic regulator in dilute sea water : keeps tissue fluid osmolarity above environmental,by concentrating saltsacross gill membranes Hyposmotic regulator: in hypersaline water keeps tissue fluid osmolarity below environmental level by active transport of NaCl from ECF out across gill membranes
31
What are freshwater teleost fish to the water they live in ?
hyperosmotic to water they live in blood is hyperosmotic compared to the environment salts must be ratained and excess water excreted
32
What are salt water teleost fish to the water they live in ?
hyperosmotic to water they live in blood is hyposmotic compared with environment water must be reatined and excess alts excreted
33
How does ion uptake occur in frehwater fish ?
freshwater animals lose ions in urine also lose ions through direct outward diffusion across the gills these need to be replaced
34
What is water conservation ?
is essential need to eliminate or conserve salt depending on the animals diet : -Herbivore :tend to conserve sdalt -Marine birds :tend to eliminate salt
35
What do some birds have ?
Nasal salt bridges excrete excess salt :secondary active transport of Cl- ions -->NaCl empties into nasal cavity As marine bird kidneys are not sufficient to maintain blood hyposmotic to seawater
36
What is filtration ?
-water and small molecules are filtered and collected in a tubule -Driven by blood pressure
37
Define Secretion and rebsorption ?
Active processes that alter the filtrate composition in tubule ## Footnote Desired function depends upon animals environemnt : Freshwater :excrete water,retain salts Marine and land animals:excrete salts,retain water
38
Excretion of nitrogenous waste ?
1. Ammonotellic: aqautic invertebrates and most bony fishes 2. Ureotelic:most amphibians 3. uricotellic :birds,insects ,reptiles
39
How does Ammonotelic excretion work ?
Metabolism of protein and nucleic acids generate nitrogenous wastes ,predominantly ammonia + not cost extra ATP to prod but highly TOXIC Aquatic animals Ammonotelic excretion : Ammonia diffuses rapidly into and is highly soluble in water usually continuosly excreted by diffusaion across gills
40
How does Ureotelic excretion work ?
animals detocify ammonia--> convert it to urea mammals all urea is highly soluble in water but animals need mechanism to concentrate urea to avoid toomuch water loss Prod urea-less toxis but costs ATP
41
What us uric acid ?
animals detocify ammonia-->uric acid Insects ,reptiles,birds water soluble ,excreted as semi-solid enables conversion of water during elimination of nitrogenous waste ## Footnote Humans are ureotelic, but we also excrete uric acid (from nucleic acid metabolism): if too much in ECF →gout. We also excrete ammonia…
42
What are flatworms ?
live in freshwater excrete water through a network of tubules ;end are fame cells -tubule +flame cell=protonephridium -ECF enters tubules by filtration ;the pressure diff causes ECF to filter through the spaces into excretory pores ## Footnote More ions are reabsorbed → urine is more dilute than ECF.
43
43
How does the excretory system of earthworms work ?
segemted :filled with fluid in cavities:Coelom -Blood is filtered :waste products diffuse directly from tissues into the coelom -Coelom fluid is swept into metanephridia through ciliated nephrostomes nephrodiapores =where dilute urine leaves