Lecture 5

Question 1

Pyruvate to lactate formula (with enzyme)

Answer 1

2 Pyruvate -> 2 Lactate
-Lactate dehydrogenase

Question 2

Pyruvate to lactate formula reversibility

Answer 2

Depends on which side has more substrate
-If there’s more lactate than pyruvate, reaction will be lactate->pyruvate

Question 3

When would pyruvate convert to lactate instead of acetyl-CoA?

Answer 3

The accumulation of pyruvate slows down glycolysis, so pyruvate converts to lactate
-The rate of pyruvate conversion is faster than then the rate of acetyl-CoA conversion

Question 4

Lactate threshold

Answer 4

Highest work rate at which blood lactate can be maintained at resting levels
-Separates moderate from heavy intensities

Question 5

Lactate Turnpoint (LTP) / Maximal lactate Steady-State (MLSS)

Answer 5

Highest work rate at which lactate dumped into blood can be proportionately cleared
-Separates heavy from severe intensities

Question 6

Can steady state be achieved in heavy intensities?

Answer 6

Yes, but it’s delayed

Question 7

Can steady state be achieved in severe intensities?

Answer 7

No