Lecture 3 Flashcards
How much ATP stored in wet muscle?
6 mmol ATP/kg
Time to exhaustion stored ATP during “all-out sprint”
~2 seconds
2 non-oxidative ATP sources:
- Phosphocreatine
- Glycolysis/glycogenolysis
Phosphocreatine process
Phosphate taken off PCr, adds P to ADP, forms ATP
PCr+ ADP <—> Cr +ATP
2 oxidative ATP sources:
- C.A.C/E.T.C.
- Fatty acids from beta oxidation
Time to exhaustion using stored ATP and PCr during “all-out sprint”
~20s
How much pyruvate and ATP produced from:
-One molecule of glucose?
-One molecule of glycogen?
glucose -> 2 pyruvate, 2 ATP
Glycogen -> 2 pyruvate, 3 ATP
How much lactate produced from pyruvate under anaerobic conditions?
Pyruvate to lactate is a 1:1 ratio, so if glucose produces 2 pyruvate, 2 lactate would be produced
Time to exhaustion using stored ATP, PCr, and Glycolysis during “all-out sprint”
~2 mins
How much ATP produced from one glucose molecule with oxidative phosphorylation?
glucose -> 32 ATP
Time to exhaustion using stored ATP, PCr, and Glycolysis and Ox Phos during “all-out sprint”
ATP resynthesis can be sustained indefinitely with Ox Phos!
How is power output affected by different energy system contributions?
Highest to lowest power output:
1. ATP
2. PCr
3. Glycolysis
4. Ox-Phos
ATP resynthesis rate (kcals/min) graph:
Peak vs Area
Peak: Highest rate at which the system can
resynthesize ATP (Peak power)
Area: Capacity of the system to resynthesize ATP
(Average power over time)
If you want to generate more immediate power, what activities should you do?
Activities that increase creatine kinase (CK) enzyme concentration and PCr stores
-Short, high-intensity
If you want to generate power over a short duration, what activities should you do?
Activities that increase glycogen stores and glycolytic enzyme concentration
-HIIT
If you want to generate power over a long duration, what activities should you do?
Activities that will increase O2 uptake/transport/utilization
