Lecture 42: Renal Pathology Flashcards

1
Q

when might a small renal core biopsy be taken

A
  • glomerulopathy

- renal tumour

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2
Q

what is acute pyelonephritis

A

acute bacterial infection of the substance of the kidney

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3
Q

what inflammatory cell might been histologically in acute pyelonephritis

A

neutrophils

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4
Q

what stain would you use to see bacteria histologically in acute pyelonephritis

A

gram stain

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5
Q

what are glomerulopathies

A
  • common cause of renal failure

- diverse group of conditions in which primary pathology is immunologically mediated injury to glomeruli

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6
Q

describe the 2 main categories of glomerulopathies

A
  • alteration of glomerular filtration barrier w/o inflammation causing primarily massive proteinuria and oedema (nephrotic syndrome)
  • inflammation in glomeruli which causes haematuria, proteinuria, hypertension (nephritic syndrome)
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7
Q

what effect does losing protein have on the body

A

causes oedema

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8
Q

what is a cyst

A

closed cavity or sac, normal or abnormal, lined by epi, and esp one that contains liquid or semi-solid material

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9
Q

what is a pseudocyst

A

cyst w/o epi lining

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10
Q

what are the two types of polycystic kidney disease and which one is more serious

A
  • autosomal recessive
  • autosomal dominant

recessive is more serious

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11
Q

what age group does each type of polycystic kidney disease affect more

A

recessive = child/infant

dominant = adult

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12
Q

what can cause severe loin pain

A

renal calculi (kidney stones)

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13
Q

give some types of kidney stones (calculi)

A
  • calcium oxalate
  • struvite
  • uric acid
  • cystine
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14
Q

what is the most common type of kidney stone

A

calcium oxalate

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15
Q

what Px might have a uric acid kidney stone

A

Px w/ gout

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16
Q

give examples of benign renal tumours

A
  • angiomyolipoma

- oncocytoma

17
Q

give examples of a malignant renal tumour

A
  • renal cell carcinoma (clear cell type)
  • renal cell carcinoma (other types)
  • transitional cell carcinoma (renal pelvis)
  • Wilm’s tumour (nephroblastoma)
18
Q

what age group does Wilm’s tumour (nephroblastoma) usually affect

A

children

- paediatric tumour

19
Q

what is a feature of renal carcinoma

A

clear cytoplasm