Lecture 4:Single gene inheritance Flashcards
Alleles is
alternate forms of a gene
Single factor cross is
Single-factor cross investigates inheritance of a single gene
Use true or pure-breeding parents
Each parent comes from a variety in which:
All members express the same characteristics
Breeding within a variety produces offspring that all show the same characteristics as each other and their parents
Choose parents that differ in one characteristic
Cross fertilization
Between pure-breeding parents produces the F1 generation
Phenotypic ratio is
Crossing follows a theoretical phenotypic ratio
Large numbers are required to observe ratios
Ratios are rarely exact
Approximations of ratios are observed
Mendels law of segregation of alleles
Explains the ratios that Mendel observed
States that two copies of a gene segregate from each other during transmission from parent to offspring
Predicting the outcome of crosses
By considering patterns of inheritance, predictions can be made about likely phenotypes and genotypes in future generations
Important in breeding
Genetic predictions are not absolute!
Predictions give only the chance or probability of certain outcomes
Importance of large numbers in genetic guesing
Probability gives theoretical expectations based on all possible outcomes being equally likely
Deviations from the expected are fewer the more times a probability event is performed: the observed result is more likely to equal the expected
Test cross is
Crossing an individual of dominant phenotype, but unknown genotype, with a recessive homozygote is a common and useful test of genotype
If about 50% of offspring show the recessive phenotype, then it can be concluded that the individual showing the dominant phenotype is heterozygous
Short legs dominant or recessive
Short legs relative to body size – a form of achondroplasia
Short legs caused by autosomal dominant allele
Overall hair length on back and ribs is determined by
Long hair is autosomal recessive
Single nucleotide change
Straight versus curly hair in genetics
Curly coat is autosomal recessive
Single base pair change
Wiry coat is caused by
(moustache or extended eyebrows) caused by an autosomal dominant allele
Alleles are caused by
Alleles segregate into gametes at meiosis and come randomly together again when gametes unite at fertilization