Lecture 1: into Flashcards
EIC is
Exercise Induced Collapse (EIC)
EIC does what
Affected dogs become weak in hind limbs and collapse after 5-20 minutes of high intensity exercise
Likely gene candidate has been identified – can be tested
EIC is inherited as an autosomal recessive
Obesity in labs is caused by
Variant of POMC gene strongly associated with weight and appetite
23% of Labradors are thought to carry at least one copy of the variant
Gene involved in hunger recognition and the feeling of being full after eating
Carrying the variant may make dogs easier to train with food
The study of genetics was found in
Study of genetics and how they control the development and maintenance of an organism
1860’s – Gregor Mendel
His observations and quantitative analysis were the foundations of genetics
Pertains to all types of organisms
3 main branches of genetics
Transmission (Mendelian)
Molecular
Population
Genetics is concerned with
Storage of biological information
How that information is expressed and regulated
How it is transmitted from parents to offspring
How that information is altered
Gene is
Hereditary unit
An information storage unit that can be replicated, expressed, regulated and transmitted
Genes are made up of and organized into
Genes are made up of DNA
Genes are organized into chromosomes
Different regions of chromosomes represent different hereditary units
Genotype is
Genetic make-up
The particular gene(s) associated with a given characteristic / trait
Phenotype is
The observable physical or biochemical characteristic
Determined by both genetic makeup and environmental influences
A “breed” is a group of organisms that share a particular phenotype
Mitosis is
The genetic material is exactly duplicated and distributed to 2 new nuclei during normal cell growth
Meiosis is
This process halves the amount of genetic material in a cell, generally in the formation of gametes for sexual reproduction
Mutation is
Altering of DNA
Chromosomes are
Packages of genes
Genetic map is
How genes are organized on a chromosome