Lecture 4-Schistosoma

Question 1

Phylum of Schistosoma

Answer 1

Platyhelmnithes

Question 2

Class of Schistosoma

Answer 2

Digenea

Question 3

Where are adult found?

Answer 3

blood vessels assoc. with intestines or bladder

Question 4

intermediate host is a __?

Answer 4

snail

Question 5

4 species that are the major causes of Schostosomiasis

Answer 5

• S. mansoni
• S. hematobulum
• S. intercalatum
• S. japonicum

Question 6

What is the only effective drug against Schistosoma?

Answer 6

praziquantel

Question 7

Which species is the most widespread?

Answer 7

S. mansoni

Question 8

Where are the eggs released?

Answer 8

intestinal lumen –> feces

Question 9

What affects the distribution of S. mansoni?

Answer 9

distribution of Biomphalaria (genus) snails

Question 10

Which species of snails transmits the most S. mansoni?

Answer 10

B. pfeifferi

Question 11

Where is S. mansoni usu. found in the globe?

Answer 11

Africa and parts of S. America and a little in N. America

Question 12

Where is S. hematobuim found in the globe?

Answer 12

Africa

Question 13

Where do adult worms of S. hematobium deposit eggs?

Answer 13

bladder of lumen

Question 14

What snails does S. hematobium use?

Answer 14

Bulinus genus

Question 15

What is the only species (that we studies) of Schistosoma that is zoonotic?

Answer 15

S. japonicum

Question 16

Where is S. japonicum usu. found?

Answer 16

Asia

Question 17

What snail species does S. japonicum use?

Answer 17

Oncomelania

Question 18

Egg laying leads to mostly what response from immune system during chronic infection?

Answer 18

Th2

Question 19

What is Th1 response for?

Answer 19

• cellular immunity

- macrophage, TNF, IFNgamma

Question 20

What is Th2 response for?

Answer 20

• humoural immunity

- B-cells, eosinophil, mast cells

Question 21

What innate immune cell is needed to switch from Th1 to Th2?

Answer 21

basophils