Lecture 4: Embryogenesis Flashcards

1
Q

What field studies development between fertilization and birth?

A

embryology

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2
Q

What field studies embryonic and other developmental processes such as stem cell biology and regeneration?

A

developmental biology

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3
Q

What % of embryos are spontaneously aborted?

A

50%

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4
Q

what % of live born children have a birth defect?

A

3-6%

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5
Q

what % of births are premature in the USA? Is this higher or lower than the % of premature births in other developed countries?

A

~12%

higher

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6
Q

what are the two leading causes of infant mortality?

A

premature births

birth defects

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7
Q

Weeks _____ of human pregnancy are known as embryogenesis (also called organogenesis), when_______ are established

A

1-8

embryogenesis

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8
Q

What are organ primordia?

A

organs in earliest recognizable stage of development

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9
Q

The embryonic period is followed by the ______ of continued _______ and ______

A

fetal period
differentiation
growth

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10
Q

What are Carnegie Stages of embryogenesis based on? What are they not based on?

A

based on external features

not based on chronological age nor size

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11
Q

How many Carnegie stages are there?

A

23

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12
Q

What is postovulatory age refer to? what terms does it replace?

A

maturity of embryo - length of time since last ovulation before pregnancy
better than gestation, pregnancy, conception

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13
Q

In the ____ week of embryogenesis, the zygote undergoes division to become a _____ and then a _______

A

first
morula
blastocyst

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14
Q

What structure implants into the uterine wall?

A

blastocyst

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15
Q

The oocyte is fertilized in the ______ region of the ________

A

ampullary

uterine tube

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16
Q

what ploidy is the zygote?

A

diploid

17
Q

how does the female anatomy help the sperm reach the oocyte?

A

muscular contractions of the uterus and uterine tube toward the ovary

18
Q

without fertilization, the oocyte degenerates _____ after ovulation

A

24 hours

19
Q

what kind of division do the oocyte and sperm undergo after fertilization?

A

mitotic

20
Q

during cleavage mitotic divisions of embryogenesis, cells are known as _______

A

blastomeres

21
Q

during cleavage mitotic divisions of embryogenesis, ______ segregates ______ fomr ______

A

compaction
inner cells
outer cells

22
Q

____ days after fertilization, the ____-cell morula is formed

A

3 days

16 cell

23
Q
How many hours post-fertilization...
2 cell stage
4 cell stage
16 cell stage
late morula stage
A

2 cell stage - 30hrs
4 cell stage - 40hrs
16 cell stage - 3 days
late morula stage - 4 days

24
Q

What stabilizes the cells during compaction of embryogenesis?

A

tight junctions between outer cells

seals off inner cells

25
Q

What does the blastocyst turn into?

A

Inner Cell Mass

Trophoblast

26
Q

What does the inner cell mass turn into?

A

Amnionic ectoderm

Embryonic epiblast

27
Q

What does the amniotic ectoderm turn into?

A

Nothing

28
Q

What does the embryonic epiblast turn into?

A

Embryonic ectoderm

Primitive streak

29
Q

What does the primitive streak turn into?

A

Embryonic endoderm

Embryonic Mesoderm

30
Q

What do the Embryonic Ectoderm, Endoderm, and Mesoderm turn into?

A

Nothing

31
Q

What does the Hypoblast turn into?

A

Extraembryonic endoderm

32
Q

What does the extraembryonic endoderm turn into?

A

Yolk sac

33
Q

The yolk sac and embryonic mesoderm combine to form _______

A

extraembryonic mesoderm

34
Q

What does the trophoblast turn into?

A

Cytotrophoblast

35
Q

What does the cytotrophoblast turn into?

A

Syncytiotrophoblast