Lecture 4 Flashcards
Musculoskeletal System
Bones and Cartilage
Includes bones, joints, muscles, ligaments, tendons, and other connective tissue
Axial Skeleton
Skull, thorax, vertebral column (axis of the body)
Appendicular Skeleton
upper and lower extremities, shoulders, and hip girdles
Bones
206 Bones
specialized form of connective tissue
Site of fat and mineral storage as well as hematopoiesis
Long bones
upper and lower extremities
Short Bones
Ankle and Wrist
Flat Bones
Scapula, skull
Irregular bones
jaw, vertebrae
Sesamoid Bones
knee cap
Periosteum
layer of connective tissue that covers compact bone surfaces
serves as the site of muscle attachment (via tendons)
The outer surface contains cells that aid in remodeling and repair (osteoblasts)
Richly supplied with blood vessels and nerve fibers
Bone Marrow
in the shaft of long bones
Red marrow is the site of hematopoiesis
osteoclasts
break down spongy bone
osteoblasts
rebuild new compact bone
osteocyte
osteoblasts surrounded by calcified extracellular material
Matrix
Extracellular material in which the osteocytes are embedded
appositional growth
new bone forms on the surface of a bone
Endochondral growth
bone eventually replaces new cartilage growth in the epiphyseal plate
growth plate
Calcium
activates vitamin D
sun, milk
Calcitonin and parathyroid hormone
regulate bone remodeling and mineralization of calcium
Vitamin D
Estrogen
inhibits formation of osteoclasts in women
Skeleton
forms from hyaline cartilage during fetal development
cartilage
tough and flexible connective tissue
PTH
promotes bone resorption by decreasing calcium
Calcitonin
increased blood calcium levels